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1)  hHGF
人肝细胞生长因子
1.
Effect of muscle electrotransfer of hHGF gene in reducing renal ischemia-reperfusion injury in rats;
人肝细胞生长因子基因肌肉电转染对大鼠肾脏缺血再灌注损伤的保护作用
2)  rhHGF
重组人肝细胞生长因子
1.
and identify recombinant human hepatocyte growth facor (rhHGF) from the culture supernatant of CHO cells.
目的对重组人肝细胞生长因子(Recombinant human hepatocyte growth facor, rhHGF)进行初步纯化及鉴定。
2.
The cDNA encoding rhHGF was amplified by PCR using cDNA library of fetal liver tissues as template,and was insert-ed,after being confirmed by DNA sequence analysis, into the vector pPIC9K to form a recombinant Pichia pastoris secretory expression vector pPIC9K-rhHGF ,which contain many copies of rhHGF gene .
利用PCR方法以人胎肝cDNA文库为模板,克隆重组人肝细胞生长因子(rhHGF)全长cDNA,经序列分析后,插入pPIC9K中,构建多拷贝串联rhHGF基因酵母分泌型表达载体pPIC9K-rhHGF,转化酵母宿主菌Pichia Pastoris GS115。
3)  Hepatocyte growth factor
肝细胞生长因子
1.
High cell density fermentation of recombinant human hepatocyte growth factor β chain bacteria;
重组人肝细胞生长因子β链工程菌的高密度发酵
2.
Protection of hepatocyte growth factor on neurons subjected to oxygen-glucose deprivation/reperfusion;
肝细胞生长因子对氧糖剥夺/再灌注神经元的保护作用
3.
Biocompatibility of combined deproteinized bone coated with hepatocyte growth factor as scaffold for osteoblasts in vitro in fetal rabbits;
胎兔成骨细胞与复合肝细胞生长因子/异种脱蛋白松质骨的体外培养
4)  Hepatocyte growth factor(HGF)
肝细胞生长因子
1.
Change of content of hepatocyte growth factor(HGF) in patients with chronic periodontitis before and after periodontal treatment;
慢性牙周炎患者基础治疗前后龈沟液中肝细胞生长因子水平的变化
2.
Objective To investigate the role of murine Hepatocyte growth factor(HGF) inducing mouse embryonic stem cells(ESC) in vitro to commitmently differentiate into hepatocyte.
目的:探讨肝细胞生长因子(HGF)诱导小鼠胚胎干细胞(ESC)体外定向分化为肝细胞的细胞功能表现。
3.
Objective To investigate the level and clinical meaning of Hepatocyte growth factor(HGF)、Soluble intercellular adhesion molecule-1(sICAM-1) in patients with cerebral infarction.
目的探讨脑梗死病人血清肝细胞生长因子(Hepatocytegrowthfactor,HGF)和可溶性细胞间粘附分子(Solubleintercellularadhesionmolecule-1,sICAM-1)的水平及临床意义。
5)  HGF
肝细胞生长因子
1.
Study of hepatic growth factor(HGF)and c-Met in carcinoma;
肝细胞生长因子及其受体在肿瘤中的研究进展
2.
Immunohistochemical Study of the Expression of HGF in Rat s Reparative Dentinogenesis;
肝细胞生长因子在大鼠修复性牙本质形成过程中的表达研究
3.
Regulation of mesangial cell proliferation and promotor activity from TGF-β1 by HGF;
肝细胞生长因子对系膜细胞增殖及TGF-β1启动子活性的影响
6)  Hepatocyte growth factor (HGF)
肝细胞生长因子
1.
Effect of Hepatocyte Growth Factor (HGF) on Morphology and Enzymic Histochemistry of Disused Muscular Atrophy;
肝细胞生长因子对废用性骨骼肌萎缩形态学及酶组织化学的影响
2.
Aim: To explore the clinical significance of the serum level of hepatocyte growth factor (HGF) in patients with multiple myeloma (MM).
目的:探讨多发性骨髓瘤(MM)患者血清肝细胞生长因子(HGF)水平变化的临床意义。
3.
Objective:To assess the concentration of hepatocyte growth factor (HGF) in the aqueous humor of glaucoma eyes,comparing with those of eyes with cataract only,used as control,in order to assess the role of HGF in the pathophysiology of glaucoma.
目的 :检测不同类型青光眼患者房水中的肝细胞生长因子 (hepatocytegrowthfactor,HGF)浓度并与单纯白内障患者作比较 ,初步探讨HGF在青光眼发病中的作用。
补充资料:肝细胞生长因子
分子式:
CAS号:

性质:存在于急性肝损伤动物血浆中的蛋白因子,能刺激肝细胞的DNA合成,且在肝再生过程中起重要作用。HGF分子量为105kD,由分子量75kD的重链(亦称α链)和分子量30kD的轻链(亦称卢链)通过二硫键构成的二聚体。HGF重链结构中包括4个克林格尔结构(Kringle structure,是由三个二硫键结成的双环状多肽结构),其中的特征序列Asn-Tyr-Cys-Arg-Asn-Pro-Asp只存在于克林格尔结构中。HGF等电点为5.5左右,对热及蛋白酶敏感,但可耐受1mol/L醋酸和0.1%SDS作用,二硫基乙醇可破坏其生物活性。它是一种肝素结合蛋白质,对肝素有较强的亲和力。其主要生理作用有:(1)启动肝再生;(2)促细胞分裂作用;(3)类似(细胞)扩散因子的功能;(4)肿瘤坏死作用。

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