1) LDLR gene
LDLR基因
1.
To investigate the methylation pattern of 12 CpG dinucleotide sites in promoter re- gion of LDLR gene in atheroselerosis patients,peripheral blood DNA samples were prepared from 61 atherosclerosis patients and 28 healthy subjects.
探讨动脉粥样硬化(Atherosclerosis,AS)病人LDLR基因启动子区12个CpG二核苷酸结构甲基化的改变。
2) LDLR knockout mice
LDLR基因缺失小鼠
3) ApoE/LDLR-DKO
ApoE、LDLR双基因缺失(apoE-/-/LDLR-/-)小鼠
4) ApoE and LDLR double knockout mice
apoE、LDLR双基因缺失小鼠
5) ApoE and LDLR gene knockout mice
ApoE和LDLR基因敲除小鼠
1.
【Results】 In animals of high-fat diet,compared with ApoE and LDLR gene knockout mice fed with a normal mouse chow,AS plaques are significantly enlagered with a large number of inflammatory cells and decreased of matrix fiberous component and thinner in fibrous caps with a changed shape and deposited a large amount of neutral lipid drops in plaque.
结论高脂饮食可加重ApoE和LDLR基因敲除小鼠AS斑块形成和Mac-3表达及炎症细胞增加,MMPs水平亦相应增加,其病变呈现出不稳定性斑块特征。
6) low density lip-protein receptor(LDLR) gene
低密度脂蛋白受体(LDLR)基因
补充资料：J基因
分子式：
CAS号：
性质： 为免疫球蛋白V区与C区之间的连接区(J区)编码的基因。
CAS号：
性质： 为免疫球蛋白V区与C区之间的连接区(J区)编码的基因。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条