Objective: to explore risk factors and the characteristic patterns of development changes of macrosomia ,we Tracked follow-up the weight, length, head circumference and chest circumference of 8 growth development monitoring time and intellective development index for aged 0-3 years macrosomia,and established normal birth weight infants as The control group.

Study of corrnary artery diameters in 210 normal children by echocardiography;

Characteristics of multifocal electroretinogram in normal children;

Research on the horizontal smooth pursuit eye movement of 300 normal children

Methods: The subjects included 9 children with epilepsy from a hospital and 36 normal children from a general kindergarten,and all of them were aged 4~5 years.