1) Platelet activating factor receptor
血小板活化因子受体
1.
Objective: Wistar rats with severe acute pancreatitis (SAP) are complicated with acute lung injury (ALI) and treated with Ginkgolide B (BN52021), then by detecting the location and expression of platelet activating factor receptor (PAF-R) in pulmonary tissues, to elucidate the function of PAF-R in the pathogenesis, the effect of BN52021 on expression of PAF-R and its mechanism.
目的:通过建立Wistar大鼠的重症急性胰腺炎(SAP)合并急性肺损伤(ALI)的模型,并采用银杏苦内酯B (BN52021)进行干预,检测血小板活化因子受体(PAF-R)在肺组织的定位、肺组织PAF-R mRNA和蛋白质表达水平的时序性变化,探讨PAF-R在SAP合并ALI发生中的作用和BN52021对PAF-R的影响及其机制。
2.
Ginkgolide B (BN52021) is a competitive antagonist of platelet activating factor receptor (PAF-R).
银杏苦内酯B(Ginkgolide B,代号为BN52021)是血小板活化因子受体(PAF-R)的特异性拮抗剂。
2) Platelet-activating factor receptor
血小板活化因子受体
1.
Expression and regulation of platelet-activating factor receptor in human keratinocytes;
血小板活化因子受体在人皮肤角质形成细胞中的表达及其调控
3) Platelet Activating Factor Receptor
血小板激活因子受体
4) Platelet-Activating Factor Receptor (PAF-R)
血小板活化因子受体(PAF-R)
5) Platelet activating factor
血小板活化因子
1.
Quantitative determination of platelet activating factor in human plasma by LC-MS/MS method;
用液相色谱-串联质谱法测定人血浆中血小板活化因子
2.
Lipopolysaccharide-induced cerebral inflammatory damage and the therapeutic effect of platelet activating factor receptor antoganist;
脂多糖诱导的大鼠脑急性炎性损伤及血小板活化因子受体拮抗剂的干预治疗效果(英文)
3.
Effects of endothelin on platelet activating factor (PAF) synthesis and release by cultured Kupffer cells from CCl_4-induced cirrhotic rats;
内皮素对肝硬化大鼠Kupffer细胞血小板活化因子生成水平的影响
6) Platelet-activating factor
血小板活化因子
1.
Role of platelet-activating factor in progesterone synthesis and vascular endothelial growth factor expression in rat luteal cells;
血小板活化因子对大鼠黄体细胞孕酮分泌及血管内皮生长因子表达的作用
2.
Analysis of 994(G→T )mutation in the plasma platelet-activating factor acetylhydrolase gene in the patients with cerebral infarction;
血小板活化因子乙酰水解酶基因994(G→T)突变与脑梗塞的关联性
3.
Plasma level of platelet-activating factor and its relation to plasma level of LPO in patients with systemic lupus erythematosus;
系统性红斑狼疮患者血浆血小板活化因子水平及其与血浆脂质过氧化物水平关系的研究
补充资料:血小板活化依赖性颗粒表面膜蛋白
分子式:
CAS号:
性质:又称血小板活化依赖性颗粒表面膜蛋白。由789个氨基酸残基组成,定位于血小板的。颗粒和内皮细胞Weibei-Palade小体(棒状小体)内,在凝血酶、组胺、补体C5b9等刺激下,α颗粒体和棒状小体膜迅速与胞膜融合而在细胞膜上表达,介导白细胞与内皮细胞的起始黏附,介导血小板与多种白细胞的结合,在炎症和血栓形成等方面起重要作用。见选择素。
CAS号:
性质:又称血小板活化依赖性颗粒表面膜蛋白。由789个氨基酸残基组成,定位于血小板的。颗粒和内皮细胞Weibei-Palade小体(棒状小体)内,在凝血酶、组胺、补体C5b9等刺激下,α颗粒体和棒状小体膜迅速与胞膜融合而在细胞膜上表达,介导白细胞与内皮细胞的起始黏附,介导血小板与多种白细胞的结合,在炎症和血栓形成等方面起重要作用。见选择素。
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参考词条