1) B7-1 gene
B7-1基因
1.
Antitumor immunning treatment stimulated by B7-1 gene transfected EL-4 lymphoma;
B7-1基因转染小鼠EL-4淋巴瘤协同IL-2作为瘤苗诱导的免疫治疗试验
2.
Methods:B7-1 gene was transfected into osteosarcoma LM8 cells with lipofectamine mediation.
方法:用脂质体(lipofectamine)介导B7-1基因和空载体pcDNA3转染LM8细胞,G418筛选得到抗性克隆,分别命名为LM8/B7-1和LM8/pcDNA3,用聚合酶链反应(RT-PCR)和流式细胞仪(FCM)鉴定转染基因的表达,采用四甲基偶氮唑蓝微量酶反应比色法(MTT)和FCM检测细胞体外增殖活性,并观察转染细胞在C3h小鼠体内致瘤能力。
3.
Mehtod: The costimulatory molecule B7-1 gene and MHC class I chain-related gene A were both key gene in activated T cell , then 108 cases of HCC were blotted by immunohistochemistry of SP method, analyzed the expression semiquantitative in hepatocytes near the tumour, hepatomas, and the cells in stroma, studied the difference .
结果B7-1基因和MICA基因在肝细胞癌、癌旁组织及间质淋巴细胞中均有表达；两种基因在癌组织和癌旁组织中均有明显的相关性(rs=0。
2) B7 gene
B7基因
3) B7-2 gene
B7-2基因
1.
Expression of IL-12 and sICAM-1 in sera and CD28 on lymphocytes and detection of B7-2 gene after inoculation of EHF vaccine;
EHF疫苗接种者IL-12、sICAM-1、CD28分子及B7-2基因检测
6) B7-H4
B7-H4基因
1.
B7-H4 is a recently described member of costimulation factor B7 family ligand which is known to be critically involved in the down regulation of antigen-specific T cell-mediated immunity.
同时检测三种卵巢癌细胞株SKOV3、3AO、A2780中B7-H4基因转录及表达情况,为进一步研究B7-H4基因的生物学特性提供细胞载体。
补充资料：J基因
分子式：
CAS号：
性质： 为免疫球蛋白V区与C区之间的连接区(J区)编码的基因。
CAS号：
性质： 为免疫球蛋白V区与C区之间的连接区(J区)编码的基因。
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