1) p21 WAF1
p21wAF1
1.
Objective To investigate the effects of histone acetylation on the expression of p53 and p21 WAF1 genes in malignant transformation of IEC-6.
方法采用我们已建立的3个转化期(化学致癌剂MNNG和诱导剂PMA共同作用6、12、24次)的IEC-6转化细胞进行培养,提取不同转化时期的IEC-6转化细胞的细胞核蛋白,采用免疫印迹检测H3乙酰化水平;并用ChIP及RT-PCR检测组蛋白H3乙酰化对p21WAF1表达的影响。
2.
Objective:To investigate the association between Cyclin D1 and metastasis and determine the relationship between Cyclin D1 proteins expression and P21 WAF1?P53 proteins in ovarian cancer.
目的:探讨细胞周期蛋白(CyclinD1)表达与卵巢癌转移的相关性和CyclinD1与P21WAF1、P53蛋白的关系。
3.
Objective:To investigate the biological features of breast carcinoma and analyze P53,P21 WAF1 and Cyclin E s functions in the genesis,progression and metastasis of breast carcinoma by the examination of P73,P21 WAF1 and Cyclin E,and their relationship with clinical-pathological feature indexes.
目的:通过检测P53蛋白、P21WAF1蛋白、CyclinE在乳腺癌中的表达及其与临床病理指标的关系,探讨乳腺癌的生物学特性,分析它们在乳腺癌的发生、转移中所起的作用。
2) P21~(WAF1)
P21WAF1
1.
Objective: To characterize the alterations of P21~(WAF1) in concurrent cancers of the esophagus and gastric cardia(CC) from the same patient.
目的:探讨同一个体食管贲门双源癌组织P21WAF1蛋白变化特征及其意义。
2.
Objective To explore the expression and clinical significance of p21~(WAF1) and CDk4 in breast cancer tissue.
目的探讨乳腺癌组织中p21WAF1及CDK4的表达及临床意义。
3.
Objective To investigate theeffect of cigarette smoke extract on theproliferation of alveolar epithelial cells type Ⅱ and its relationship with the expression of P21~(WAF1).
目的探讨香烟烟雾提取物(cigarette smoke extract,CSE)对人类肺泡Ⅱ型上皮细胞来源的A549细胞增殖的影响及其与P21WAF1表达的关系。
3) p21 WAF1/CIP1
p21WAF1/CIP1
1.
Objective:In order to evaluate the significance of the expression of p21 WAF1/CIP1 and PCNA (proliferating cell nuclear antigen) in hypopharyngeal and laryngeal squamous cell carcinoma.
目的:探讨p21WAF1/CIP1和抑制增殖细胞核抗原(PCNA)的表达与下咽癌、喉癌的分级、转移及预后 的关系,了解p21WAF1/CIP1在下咽癌、喉癌发生、发展中的作用以及与PCNA的相关性。
2.
Objective To verify the binding of p53to p21 WAF1/CIP1 gene promoter and detect its binding to hsp90βgene promoter in vivo.
目的验证抑癌基因表达产物p53蛋白在体内是否结合于p21WAF1/CIP1基因的启动子区,并检测p53蛋白对热休克蛋白hsp90β基因启动子区的结合情况。
3.
Resver atrolalso significantly improved the expression of P21 WAF1/CIP1 mRNA and protein.
目的:探讨白藜芦醇(Resvratrol,Res)在体外对肝癌细胞分化及相关周期蛋白依赖激酶抑制因子P21WAF1/CIP1的影响。
4) p21WAF1/CIP1
p21wAF1/CIPl
5) P21~(WAF1/CIP1)
P21WAF1/CIP1
1.
Objective To study the interaction between P53 and P21~(WAF1/CIP1) protein in cervical carcinoma of Uigur Women in Xinjiang.
采用免疫组化方法检测80例维族宫颈癌组织和34例维族正常宫颈组织中P53和P21WAF1/CIP1蛋白表达情况,探讨P53和P21WAF1/CIP1蛋白在新疆维吾尔族妇女宫颈癌中发生、发展中的作用以及相互关系。
6) P 21 WAF1/CIP1
P21WAF1/CIP
补充资料：1,4,9(11),16-Pregnatetraene-21-ol-3,20-dione-21-acetate
分子式：暂无
分子量：暂无
CAS号：暂无
性质：暂无
制备方法：暂无
用途：激素类药。
分子量：暂无
CAS号：暂无
性质：暂无
制备方法：暂无
用途：激素类药。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条