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1)  cross-linked N-telopeptides of Type 1 collegen
Ⅰ型胶原氨基末端肽
1.
[Objective] To study the relationships of smoking and bone alkaline phosphatase (BAP), serum osteocalcin (sOC) and cross-linked N-telopeptides of type 1 collegen(sNTX)and bone mineral density in healthy men aged 20~80.
方法用DXA仪测定腰椎及髋部BMD,用ELISA测定389例20~80岁健康男性血清骨特异性碱性磷酸酶(sBAP)、血清骨钙素(sOC)和Ⅰ型胶原氨基末端肽(sNTX)。
2.
Objective:To study the relationships of smoking and bone alkaline phosphatase(BAP),cross-linked N-telopeptides of type 1 collegen(sNTX)and bone mineral density in healthy men aged 20~80.
方法:用DXA仪测定腰椎及髋部BMD,用ELISA测定389例20~80岁健康男性血清骨特异性碱性磷酸酶(sBAP)和Ⅰ型胶原氨基末端肽(sNTX)。
2)  N-telopeptides of type Ⅰ collagen
尿Ⅰ型胶原氨基末端肽
1.
Background and purpose:The role of urine N-telopeptides of type Ⅰ collagen(uNTX) and serum bone spesifi c alkaline phosphatase(sBAP)was confi rmed in osseous metastasis of solid tumors.
背景与目的:近年尿Ⅰ型胶原氨基末端肽(uNTX)、血清骨特异性碱性磷酸酶(sBAP)在监测实体瘤骨转移的作用已得到肯定,本研究旨在了解其在多发性骨髓瘤(multiple myeloma,MM)的意义。
3)  N-telopeptides of type I collagen
Ⅰ型胶原交联氨基末端肽
1.
Objective:To study the clinical significance of examining serum pyridinoline cross-linked N-telopeptides of type I collagen(NTx) and serum bone sialoprotein(BSP) in diagnosing bone metastasis of lung cancer and breast cancer.
目的:探讨骨代谢生化指标血清Ⅰ型胶原交联氨基末端肽(N-telopeptide of typeⅠcollagen,NTx)和骨涎酸蛋白(bone sialoprotein,BSP)的检测对肺癌和乳腺癌骨转移的临床意义。
2.
Objective: To study the clinical significance of the quantitative assays of serum pyridinoline cross-linked N-telopeptides of type I collagen (NTx) and serum bone sialoprotein (BSP) to diagnose bone metastases from paytients with lung cancer and breast cancer.
实验目的: 在肺癌和乳腺癌患者中,探讨骨代谢生化指标血Ⅰ型胶原交联氨基末端肽(NTx)和骨唾液酸蛋白(BSP)的定量检测对恶性肿瘤骨转移的临床意义。
4)  Ⅰ Collagen cross linked c-telopeptide(ICTP)
Ⅰ型胶原羟基末端肽
5)  Type I collagen cross-linked telopeptide
Ⅰ型胶原羧基末端肽
6)  procollagen type I ca rboxy-terminal peptide
Ⅰ型前胶原羧基末端肽
补充资料:前胶原肽酶
分子式:
CAS号:

性质:是存在于细胞外,对前胶原进行加工的酶。它包括两种酶:(1)N-末端前胶原肽酶,其分子量为260 000,能够切除前胶原的氨基前肽;(2)C-末端前胶原肽酶,其分子量为80 000,属于糖蛋白,能切除前胶原的羧基前肽。两种酶均需要二价阳离子,如Ca2+。

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