1) small RNA
小RNA
1.
Advances in the small RNA of plant;
植物小RNA的研究进展
2.
Eukaryotes produce various types of 19-30 nt small RNAs,which act as guides to the regulation of gene expressions,such as mRNA degradation and translational repression.
真核细胞能产生一类长度19～30个核苷酸(nt)的小RNA,这些小RNA能在降解mRNA及翻译抑制等方面起靶向作用。
3.
The researches on small RNAs used to focus mainly on mammals in the past,but with the development of bioinformatics and molecular biology,some small RNAs have been found in prokaryotes.
小RNA(smallRNAs或sRNAs)是一类长度在40至400个核苷酸、广泛存在于从细菌到哺乳动物多种不同的生物体内、执行多种生物学功能的非编码的RNA分子。
2) microRNA
小RNA
1.
Objective:To observe the change of microRNA(miRNA) expression on acute cerebral ischemia in rats.
目的:观察脑缺血急性期大鼠脑组织小RNA(microRNA,miRNA)差异表达。
3) Small interfering RNA
小干扰RNA
1.
Construction of magnetic small interfering RNA nanoparticles and effects of its transfection on silencing survivin gene expression and inducing human bladder cancer cell apoptosis;
磁性小干扰RNA纳米微粒的制备及其转染人膀胱癌细胞对沉默survivin基因表达影响的研究(英文)
2.
Suppression of vascular endothelial growth factor expression by vector-based small interfering RNA in human tongue squamous carcinoma cell line Tca8113;
载体携带小干扰RNA抑制Tca8113细胞血管内皮生长因子的表达
3.
Targeting the 5 -Non-translated Region of Hepatitis C Virus by Intracellularly Expressed Small Interfering RNA;
细胞内表达的小干扰RNA靶向丙肝病毒5’保守区的研究
4) siRNA
小干涉RNA
1.
Objective To explore the relationship between specific silencing effect of siRNA that targets latent membrane protein 1(LMP1) coding gene on the proliferation and apoptosis of EBV positive gastric epithelium cells.
目的探讨化学合成小干涉RNA(siRNA)对Epstein-Barr病毒(EBV)潜伏膜蛋白1(LMP1)阳性胃上皮(GT38)细胞LMP1编码基因表达的抑制作用,以及对细胞增殖和凋亡的影响。
2.
On the basis of previous study,in which two target sequences with favorable RNAi effect on HER2 were identified, a series of dual promoter siRNA-expressing vectors c.
在以往鉴定的对HER2有良好RNAi效应的靶序列的基础上,构建了一系列U6和H1双启动子小干涉RNA(siRNA)表达载体,并转染HER2高表达乳腺癌SKBR3细胞定量测定了其HER2下调效应。
3.
Different siRNA(small interference RNA),as trigger of RNAi, can lead to different level of RNA interference.
RNAi)可以抑制诸多真核基因的表达,小干涉RNA(smallintmferenceRNA,siRNA)是RNA干涉的引发物,不同的siRNA可以引导不同水平的RNA干涉,不同种细胞中siRNA的寡核苷酸链的性质也有很大的不同。
5) small interfering RNA(siRNA)
小干扰RNA
1.
Objective: To investigate the inhibitory effect of small interfering RNA(siRNA),targeting human papillomavirus(HPV) 18 E6 gene,on expression of E6,E7 gene of HPV 18 and on P53 protein expression in cervical cancer Hela cells.
目的:以人乳头瘤病毒(human papillomavirus,HPV)18型E6基因为靶点,研究小干扰RNA(small interference RNA,siRNA)对宫颈癌Hela细胞株HPV18基因组中恶性转化基因E6、E7的抑制作用及对细胞内P53蛋白表达的影响。
2.
Objectives:To investigate the expressions of matrix metalloproteinase(MMP) -2,-9 and tissue inhibitors of metalloproteinase (TIMP) -1,-2 in human tongue squamous cell carcinoma(Tca8113) in virto and in vivo,after suppressed the expression of vascular endothelial growth factor(VEGF) by vector-based small interfering RNA(siRNA).
目的:利用小干扰RNA(small interfering RNA,siRNA)抑制人舌癌Tca8113细胞血管内皮生长因子(vascular endothelialgrowth factor,VEGF)表达,观察其对培养细胞和移植瘤基质金属蛋白酶(matrix metalloproteinases,MMPs)-2,-9及基质金属蛋白酶抑制剂(tissue inhibitors of metalloproteinases,TIMPs)-1,-2蛋白表达的影响。
3.
In this study, specific small interfering RNA(siRNA) expressing vectors of ATGL gene was constructed.
1-CMVneo干扰载体中,构建猪ATGL基因的小干扰RNA(siRNA)真核表达载体,并对其进行PCR、双酶切及测序鉴定。
6) MicroRNA
微小RNA
1.
Progresses on the study of microRNA′s regulation mechanism;
微小RNA调控靶基因作用机制的研究进展
2.
MicroRNA depresse the expression of MAD2 gene in trophoblastic cells;
微小RNA抑制胚胎细胞MAD2基因的表达
补充资料：(+)RNA病毒
分子式：
CAS号：
性质：(1)双链DNA分子中，碱基序列与转录产物一致者为正链，也称编码链、非模板链；(2)具mRNA功能、进入宿主细胞后可直接作为模板合成病毒蛋白质的单链RNA病毒，称正链RNA病毒或(+)RNA病毒。此类病毒在生长周期中，先以亲代RNA为模板合成RNA指导的RNA聚合酶(RDRP)及病毒外壳蛋白，然后通过RDRP催化合成病毒RNA互补负链，即双链复制型(RF)，再以RF的负链为模板合成子代RNA正链；(3)单链DNA病毒。
CAS号：
性质：(1)双链DNA分子中，碱基序列与转录产物一致者为正链，也称编码链、非模板链；(2)具mRNA功能、进入宿主细胞后可直接作为模板合成病毒蛋白质的单链RNA病毒，称正链RNA病毒或(+)RNA病毒。此类病毒在生长周期中，先以亲代RNA为模板合成RNA指导的RNA聚合酶(RDRP)及病毒外壳蛋白，然后通过RDRP催化合成病毒RNA互补负链，即双链复制型(RF)，再以RF的负链为模板合成子代RNA正链；(3)单链DNA病毒。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条