Pharmacokinetics and tissue distribution of daurisoline in rabbits;

Synthesis and Ca~(2+)-channel Blocking Activities of Daurisoline Derivatives;

Study on the pharmacokinetic-pharmacodynamic characteristics of daurisoline and dauricine in Beagle dogs;

Determination of the contents of Dauricine in refined total alkaloids of Rhizoma Menispermi capsule by HPLC;

Study on stability of dauricine content of powder injection of total alkaloids of menispermum dauricum;

Therapeutic Effects of Dauricine on Early Afterdepolariztions Induced by Dofetilide;

Antimutagenic activity of phenolic alkaloids from menispermum dauricum;

Study on the Function of Phenolic alkaloids from Menispermum dauricum on Anti-anoxia Ability and Anti-ischemia/Reperfusion Cerebral Injury in Mice;

Protective effects of phenolic alkaloids from Menispermum dauricum on inflammatory injury following focal cerebral ischemia-reperfusion in rats;

Effect of PAMD on the proliferation of K562、BXPC-3;

To explore the expressions of Bcl-2 mRNA and Bax mRNA in the cortical neuron induced after ischemia modulated by PAMD.

Objective:To observe the anti-tumor effect of PAMD(phenolicalkaloids of Menispermum dauricum)on tumor-bearingmice,so that we can study the content of TNF-αin peripheral bloodof tumor-bearing mice to observe the effect of on expression ofgene and protein content of k-ras and DPC4 in tumour tissues oftumor-bearing mice and to observe the effect on apoptosis rate ofBXPC-3.