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1)  daurisoline
蝙蝠葛苏林碱
1.
Pharmacokinetics and tissue distribution of daurisoline in rabbits;
蝙蝠葛苏林碱在兔体内的药代动力学及组织分布(英文)
2.
Synthesis and Ca~(2+)-channel Blocking Activities of Daurisoline Derivatives;
蝙蝠葛苏林碱衍生物的合成及钙通道阻滞活性的研究
3.
Study on the pharmacokinetic-pharmacodynamic characteristics of daurisoline and dauricine in Beagle dogs;
蝙蝠葛苏林碱和蝙蝠葛碱犬体内药动学-药效学结合研究
2)  Daurisoline
北豆根苏林碱,蝙蝠葛苏林碱
3)  Dauricine
蝙蝠葛碱
1.
Determination of the contents of Dauricine in refined total alkaloids of Rhizoma Menispermi capsule by HPLC;
高效液相色谱法测定北豆根精制总碱胶囊中蝙蝠葛碱含量
2.
Study on stability of dauricine content of powder injection of total alkaloids of menispermum dauricum;
北豆根总碱粉针剂中蝙蝠葛碱质量分数稳定性
3.
Therapeutic Effects of Dauricine on Early Afterdepolariztions Induced by Dofetilide;
蝙蝠葛碱对多非利特诱发的早后除极的治疗作用
4)  methylisocorydine
蝙蝠葛林
5)  phenolic alkaloids from Menispermum dauricum
蝙蝠葛酚性碱
1.
Antimutagenic activity of phenolic alkaloids from menispermum dauricum;
蝙蝠葛酚性碱抗突变作用的研究
2.
Study on the Function of Phenolic alkaloids from Menispermum dauricum on Anti-anoxia Ability and Anti-ischemia/Reperfusion Cerebral Injury in Mice;
蝙蝠葛酚性碱对小鼠耐缺氧能力及抗缺血复灌性脑损伤的作用
3.
Protective effects of phenolic alkaloids from Menispermum dauricum on inflammatory injury following focal cerebral ischemia-reperfusion in rats;
蝙蝠葛酚性碱对大鼠局灶性脑缺血-再灌注继发炎性损伤的保护作用
6)  PAMD
蝙蝠葛酚性碱
1.
Effect of PAMD on the proliferation of K562、BXPC-3;
蝙蝠葛酚性碱对K562、BXPC-3增殖的影响
2.
To explore the expressions of Bcl-2 mRNA and Bax mRNA in the cortical neuron induced after ischemia modulated by PAMD.
探讨蝙蝠葛酚性碱预处理对脑缺血后大脑皮质神经元Bcl-2和Bax基因表达的影响。
3.
Objective:To observe the anti-tumor effect of PAMD(phenolicalkaloids of Menispermum dauricum)on tumor-bearingmice,so that we can study the content of TNF-αin peripheral bloodof tumor-bearing mice to observe the effect of on expression ofgene and protein content of k-ras and DPC4 in tumour tissues oftumor-bearing mice and to observe the effect on apoptosis rate ofBXPC-3.
目的:通过蝙蝠葛酚性碱(PAMD)抗肿瘤活性的体内实验研究,观察PAMD对胰腺癌(BXPC-3)荷瘤小鼠肿瘤的抑制作用及外周血TNF-α含量的影响;PAMD对胰腺癌(BXPC-3)荷瘤小鼠肿瘤组织中k-ras和DPC4基因及蛋白表达的影响;PAMD对胰腺癌(BXPC-3)细胞凋亡率的影响。
补充资料:蝙蝠葛苏林碱
分子式:
CAS号:

性质:又称蝙蝠葛苏林碱。属双苄基四氢异喹啉类生物碱。乳黄色粉末(由环己烷),含1/3分子环己烷。熔点96~102℃。旋光度-129°(c=0.65,甲醇)。存在于防己科植物蝙蝠葛[Menispermum dauricum DC.]的根茎中,也可化学合成。动物实验及临床实践验证其溴甲基化物注射液(D610)有肌松作用,属非去极化型肌松剂,且对实质性脏器无明显损害,安全范围较大。

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