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1)  M1-acetylcholine receptor
M1型胆碱能受体
1.
Objective To investigate the effect of nucleic acid on M1-acetylcholine receptor and the possible mechanism resisting hepatic fibrosis induced by carbon tetrachloride(CCl4).
采用光镜观察肝组织病理学改变;运用免疫组织SP法?逆转录聚合酶链反应(RT-PCR)和Western-blot方法检测各组肝组织M1型胆碱能受体(M1-AChR)不同水平的表达情况。
2)  Cholinergic (M) receptor
胆碱能M型受体
3)  nicotinic acetylcholine receptors
烟碱型胆碱能受体
1.
The learning and memory abilities of the rats were assessed through Morris water maze behavioral test, and the expressions of nicotinic acetylcholine receptors and ChAT were observed by Western blotting and immunohistochemistry, respectively.
水迷宫实验检测大鼠学习记忆能力;West-ern blot实验检测大鼠海马烟碱型胆碱能受体的表达;免疫组化观察大鼠脑内ChAT的表达。
2.
The learning and memory abilities of the rats were assessed through Morris water maze behavioral test,and the expressions of nicotinic acetylcholine receptors and GFAP were observed by Westem blotting and immunohistochemistr.
水迷宫实验检测大鼠学习记忆能力;Western blotting实验检测大鼠海马烟碱型胆碱能受体的表达;免疫组化观察大鼠脑内胶质纤维酸性蛋白(GFAP)的表达。
4)  cholinergic receptor
胆碱能受体
1.
Methods Rat peritoneal macrophages were collected and exposed to muscarinic cholinergic receptor antagonist atropine or α-bungarotoxin,an antagonist specifically binds the α7 subunit of nicotinic cholinergic receptor.
方法采集大鼠腹腔巨噬细胞,先给予M样胆碱能受体拮抗剂阿托品或N样胆碱能受体α7亚基特异性拮抗剂α-银环蛇毒素,15min后给予卡巴胆碱或N样胆碱能激动剂烟碱,15min后再给予LPS刺激,4~6h后取细胞培养上清液,ELISA法检测促炎细胞因子TNF-α、IL-6水平和抗炎细胞因子IL-10水平。
5)  Cholinergic receptors
胆碱能受体
6)  neuronal nicotinic acetylcholine receptor
烟碱型胆碱受体
1.
Effects of Huoyi decoction(活忆饮) on expressions of amyloid-βpeptide1-40 and neuronal nicotinic acetylcholine receptor in different brain sections of rat′s model with Alzheimer′s disease;
活忆饮对阿尔茨海默病模型大鼠β-淀粉样肽1-40和烟碱型胆碱受体的影响
补充资料:M胆碱受体激动药
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CAS号:

性质:又称M胆碱受体激动药,节后拟胆碱药。一类作用与副交感神经兴奋时效应类似的药物。药物与副交感神经节后纤维所支配效应器上的M胆碱受体结合,并激动之,产生M样作用。表现为心脏抑制,内脏平滑肌收缩,腺体分泌增加,瞳孔缩小等效应。代表药是匹鲁卡品,对眼和腺体作用最明显,主要用于眼科治疗青光眼。不良反应主要由于吸收后的M样作用引起,可用阿托品治疗。

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