1) hypoxia response elements
缺氧反应元件
2) Hypoxia responsive element
缺氧反应元件
1.
Hypoxia responsive element regulated herpes simplex virus-thymidine ktnase system enhances killing effect of gancyclovir on Ewing s sarcoma cell line under hypoxic condition;
缺氧反应元件增强单纯疱疹病毒胸苷激酶/GCV对乏氧环境Ewing肉瘤细胞杀伤作用的研究
2.
To improve the effectiveness of radiotherapy and chemotherapy to these tumours, a eukaryotic expression vector expressing herpes simplex virus-thymidine kinase (HSV-TK) regulated by hypoxia responsive element (HRE) under hypoxia was constructed.
本研究拟构建一种由缺氧反应元件(hypoxia responsive element,HRE)调控的单纯疱疹病毒胸苷激酶(herpes simplex virus-thymidine kinase,HSV-TK)基因的真核表达载体,观察HRE能否增强HSV-TK/丙氧鸟苷(gancyclovir,GCV)系统对乏氧环境中的人Ewing肉瘤细胞系(SK-ES-1细胞)的杀伤作用,为弥补放、化疗的不足探索有效的治疗方法。
3) antioxidant response element
抗氧化反应元件
1.
A cis-acting transcriptional regulatory element, designated as antioxidant response element (ARE) or electrophile response element (Ep.
一个被称为抗氧化反应元件(antioxidant response element,ARE)或亲电子反应元件(electrophile response element,EpRE)的顺式转录调控元件,可以介导诸如亚铁血红素加氧酶1、γ-谷氨酰半胱氨酸合成酶、硫氧还蛋白还原酶、谷胱甘肽-S转移酶和NAD(P)H:苯醌氧化还原酶等基因的转录。
2.
The important elements of Nrf2-ARE signal pathway are nuclear factor erythroid-2p45-related factor2(Nrf2),antioxidant response element(ARE) and Kelch-like ECH-associated protein1(Keap1).
Nrf2-ARE信号转导通路是当前研究的热点,其核心分子包括核转录因子红细胞系-2p45(NF-E2)相关因子-2(nuclear factor erythroid-2p45-related factor2,Nrf2)、抗氧化反应元件(antioxidant response element,ARE)和Kelch样环氧氯丙烷相关蛋白-1(Kelch-like ECH-associated protein 1,Keap1)。
4) hypoxic response element
低氧反应元件
1.
Delayed disappearance of h-VEGF_(165) mRNA and protein under regulation of hypoxic response element;
低氧反应元件调控下h-VEGF_(165)基因表达及其蛋白产物的延迟消失
2.
Objective To generate and identify an AAV-VEGF165vector using a hypoxic response element promoter to control the expression of hVEGF165.
目的包装及鉴定低氧反应元件(HRE)启动子控制下缺氧诱导目的基因hVEGF165基因表达的2型重组腺相关病毒。
5) hypoxic response elements
低氧反应元件
1.
Objective To investigate how the nine copies hypoxic response elements(9HRE) regulate the expression of human vascular endothelial growth factor 165(hVEGF_(165)) gene transferred by adeno-associated vector into ischemia and reperfusion myocardium in vivo.
目的探讨低氧反应元件(hypoxic response element,HRE)对缺血、复灌心肌转导人血管内皮生长因子165(human vascular endous growth factor 165,hVEGF165)基因表达的调控作用。
6) anti-oxidative response element(ARE)
抗氧化反应元件(ARE)
补充资料:低血流性缺氧
低血流性缺氧
又称"循环性缺氧"。缺氧的一个类型。指血循环障碍,向组织中输送氧量减少的一种状态。是由于动脉血流入组织不足或静脉血流不畅所引起。其特点为动脉血氧分压、氧含量、氧容量、血氧饱和度正常,而静脉血内则显著降低。临床表现为局限或全身紫绀。瘀血性缺氧,紫绀更为明显。
说明:补充资料仅用于学习参考,请勿用于其它任何用途。
参考词条