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1)  Extended-spectrum β-lactamase
超广谱β内酰胺酶
1.
The genotypes of extended-spectrum β-lactamases in 119 clinical isolates of Proteus mirabilis
奇异变形杆菌产超广谱β内酰胺酶基因检测
2.
Antimicrobial resistance and extended-spectrum β-lactamases genotypes of Shigella isolates in Shanghai
上海地区志贺菌耐药性及超广谱β内酰胺酶基因型分析
2)  Extended-spectrum beta-lactamases
超广谱β内酰胺酶
1.
Objective:To evaluate the in vivo antibacterial effects of combination of sulbactam with cefotaxim(1;1,2;1,4:1 and 8:1)in the treatment of mice septicemia caused by the pathogenic microor- ganisms producing extended-spectrum beta-lactamases(ESBLs).
结果:头孢噻肟-舒巴坦在1:1,2:1和4:1质量配比时对大肠埃希菌、肺炎克雷伯菌产超广谱β内酰胺酶(ESBLs)菌株的体内抗菌作用显著优于头孢噻肟-舒巴坦(8:1)及头孢噻肟单剂,ED_(50)值及ED_(95)值仅为头孢噻肟单剂的1/6。
2.
OBJECTIVE To investigate resistant phenotype of Extended-spectrum beta-lactamases producing Escherichia coli in our hospital.
目的了解我院产超广谱β内酰胺酶大肠埃希菌耐药基因表达状况。
3)  ESBLs
超广谱β内酰胺酶
1.
Methods Taking agar gel diffusion test to determine the 1120 strains of pathogenic bacteriums;Taking double paper diffusion screening test to determine extended spectrum β lactamases(ESBLs)of Escherichia coli and Klebsiella pneumoniae;The results of 39 strains samplings with bronchof.
方法采用琼脂扩散法敏感试验,测定我院ICU分离的共1120株病原菌;采用酶抑制剂增强纸片测定大肠埃希氏菌和肺炎克雷伯菌的超广谱β内酰胺酶(ESBLs);运用经纤支镜采样39株,与常规结果进行对照。
2.
Objective To analyze the actuality and the drug resistance of Gram negative bacilli which produce extended-spectrum β-lactamases(ESBLs), and to guide the proper use of antibiotics.
目的:分析革兰阴性杆菌产超广谱β内酰胺酶(ESBLs)的现状和耐药性,指导临床合理使用抗生素。
3.
Objective: To investigate the prevalence and genotype ofplasmid-mediated cephalosporinase (AmpC)β-lactamases andextended-spectrum-β-lactamases(ESBLs) in clinical Escherichia coliand Klebsiella pneumoniae.
目的调查肺炎克雷伯菌、大肠埃希菌中质粒介导头孢菌素酶(AmpC酶)和超广谱β内酰胺酶(ESBLs)的基因型分布、耐药性及流行趋势。
4)  Extended-spectrum β-lactamases
超广谱β内酰胺酶
5)  Extended spectrum β lactamase
超广谱β内酰胺酶
6)  ESBLs
超广谱酶β-内酰胺酶
1.
Relationship between Class 1 Integron and Resistance in Clinical ESBLs-producing Escherichia Coli Strains;
产超广谱酶β-内酰胺酶大肠埃希氏菌Ⅰ类整合子检测与耐药性关系
补充资料:β-内酰胺酶
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性质:细菌产生的能水解β-内酰胺类抗生素的本科,由于β-内酰胺本科的水解,β-内酰胺类抗生素失活。显色头孢菌素头孢硝噻吩(nitrocefin)的溶液呈浅黄色,当结构中的β-内酰胺环被打开时,溶液呈由浅黄色变成红色,因而可利用这种头孢菌素显色的特点,特异证实β-内酰胺酶的存在,β-内酰胺酶以其主要水解对象可分为青霉素酶、头孢菌素酶、广谱酶、超广谱酶。

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