1) glutamic acid decarboxylase antibody
谷氨酸脱羧酶抗体
1.
Methods The glutamic acid decarboxylase antibody(GADA) and islet cell antibody(ICA) were measured in 106 patients with type 2 diabetes mellitus, and the correlations were compared between age, body mass index(BMI),symptom and antibody positivity.
②方法 检测 10 6例初诊的 2型糖尿病病人的谷氨酸脱羧酶抗体 (GADA)和胰岛细胞抗体(ICA) ,比较发病年龄、体质量指数 (BMI)和典型症状与抗体阳性的关系 ,并进行为期 1。
2.
Objective:To study the variability of the glutamic acid decarboxylase antibody(GADA) and protein tyrosine phosphatase antibody(IA-2A) during the course of acute-onset type 1 diabetes mellitus patients and their relationships with clinical features.
目的:观察谷氨酸脱羧酶抗体(glutamic acid decarboxylaseantibody,GADA)和蛋白酪氨酸磷酸酶抗体(protein tyrosinephosphatase antibody,IA-2A)在急性起病的1型糖尿病(T1DM)患者病程中的变化趋势及探讨不同的变化趋势与临床特征的关系。
3.
Objective To explore the distribution of glutamic acid decarboxylase antibody(GADA),islet cell antibody(ICA)in patients with type 2 diabetes,and to study their characteristics and the factors related to each other.
目的探讨2型糖尿病患者谷氨酸脱羧酶抗体(glutamic acid decarboxylase antibody,GADA)、胰岛细胞抗体(islet cell antibody,ICA)分布特点及与影响因素的相关性。
2) GAD-Ab
谷氨酸脱羧酶抗体
1.
Methods 142 cases of elderly patients with diabetes screened by glutamic acid decarboxylase autoantibodies (GAD-Ab) were divided into two groups,17 cases in GAD-Ab positive group and 125 cases in GAD-Ab negative group.
目的比较老年糖尿病患者中血谷氨酸脱羧酶抗体(GAD-Ab)阳性者与阴性者其临床特征及生化检测的差异。
2.
Objective To investigate the β-cell function status and possible mechanism of insulin resistance in patients with type 2 diabetes through studies on the changes of serum APN, insulin, CRP, leptin, insulin antibody and glutamic acid decarboxy lase antibody (GAD-Ab) levels after one year of treatment.
目的:通过对2型糖尿病患者血清中脂联素(APN)、胰岛素、C-反应蛋白、瘦素(Leptin)、胰岛素抗体及谷氨酸脱羧酶抗体(GAD-Ab)检测分析,探讨胰岛β细胞功能和胰岛素抵抗的机理,为其早期诊断治疗提供依据。
3.
Objective] To explore the value of combined detection of GAD-Ab、ICA and IAA in serum of diabetes mellitus patients .
[目的 ]探讨糖尿病患者血清谷氨酸脱羧酶抗体 (GAD -Ab)、胰岛细胞抗体 (ICA)和胰岛素自身抗体 (IAA)的联合检测在临床中的重要意义。
4) glutamic acid decarboxylase antibodies
谷氨酸脱羧酶抗体
1.
Objective: To evaluate the significance of combined determination of glutamic acid decarboxylase antibodies(GADA), islet cell antibodies(ICA) and insulin autoantibodies(IAA) in precaution of type 1 diabetes mellitus.
目的:评价联合检测谷氨酸脱羧酶抗体(GADA)、胰岛细胞抗体(ICA)和胰岛素自身抗体(IAA)对1型糖尿病的早期诊断价值。
2.
Glutamic acid decarboxylase antibodies (GADA), islet cell antibodies (ICA), insulin autoantibodies (IAA) and the serum C-peptide in 188 patients with recently diagnosed diabetes were measured.
目的:检测胰岛素自身抗体(IAA)、胰岛细胞抗体(ICA)、谷氨酸脱羧酶抗体(GADA)和血清C肽,筛选出成年隐匿型自身免疫性糖尿病(LADA)对其进行早诊断、早治疗。
5) Glutamic acid decarboxylase autoantibody
谷氨酸脱羧酶抗体
1.
Objective To test the frequency of cytoplasmic islet cell autoantibody (ICA), glutamic acid decarboxylase autoantibody (GADA), protein tyrosine phosphatase-like IA-2 autoantibody (IA-2A) or multiple autoantibodies in type I diabetes patients with different courses and to evaluate its value for pathogenesis and diagnosis of the disease.
目的 观察不同病程I型糖尿病患者中血清胰岛细胞抗体(ICA)、谷氨酸脱羧酶抗体(GADA)和酪氨酸磷酸酶抗体(IA-2A)的阳性率,探讨胰岛自身抗体在本病发病机制和诊断中的作用。
6) GADA
谷氨酸脱羧酶抗体
1.
The Effects of Metformin on the Serum Levels of IL-6, CRP and the Function of β-cell in IGT Patients with Different Expression Levels of GADA
二甲双胍对不同谷氨酸脱羧酶抗体表达糖耐量受损患者血清白细胞介素-6、C反应蛋白及胰岛β细胞功能的影响
补充资料:谷氨酸脱羧酶抑制剂
分子式:
CAS号:
性质:能够抑制谷氨酸脱羧酶活性的一类化合物。如二羟基或三羟基苯甲酸以及某些与苯二甲酸相关的化合物,都能非特异性抑制谷氨酸脱羧酶,其中丰加链霉菌1039菌株产生的4,5-二羟基间苯二甲酸活性最高,是一种竞争性抑制剂,小鼠静脉给药可引起脑部γ-氨基丁酸含量下降,谷氨酸脱羧酶抑制剂是研究γ-氨基丁酸在脑神经系统中功能的很好工具。
CAS号:
性质:能够抑制谷氨酸脱羧酶活性的一类化合物。如二羟基或三羟基苯甲酸以及某些与苯二甲酸相关的化合物,都能非特异性抑制谷氨酸脱羧酶,其中丰加链霉菌1039菌株产生的4,5-二羟基间苯二甲酸活性最高,是一种竞争性抑制剂,小鼠静脉给药可引起脑部γ-氨基丁酸含量下降,谷氨酸脱羧酶抑制剂是研究γ-氨基丁酸在脑神经系统中功能的很好工具。
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