1) Osteogenic differentiation
成骨分化
1.
The influence of proliferation and osteogenic differentiation of vancomycin on the rabbits MSCs.;
不同浓度万古霉素对兔骨髓间充质干细胞增殖和成骨分化的影响
2.
Study for the capability of osteogenic differentiation from distinct transfer of culture power adult mesenchyme stem cell;
不同传代倍数成人间充质干细胞成骨分化能力的研究
3.
Effects of age on proliferation and osteogenic differentiation of human mesenchymal stem cells in vitro;
人骨髓间充质干细胞体外增殖及成骨分化的增龄变化
2) osteoblast differentiation
成骨分化
1.
Aim To investigate the effect of rhBMP-2m on osteoblast differentiation so as to find out a osteoblast-specific marker for quantitatively determining rhBMP-2m' s activity.
目的进一步探讨rhBMP-2的促细胞成骨分化作用,以期找到合适的成骨分化标志作为rhBMP-2的定量活性测定指标。
5) osteoblast differentiation
成骨细胞分化
1.
Cbfa1/Runx2 and regulation of osteoblast differentiation;
Cbfa1/Runx2与成骨细胞分化调控
2.
Runx2 is a transcription factor essential for osteoblast differentiation and bone formation.
Runx2基因编码成骨细胞特异性转录因子,调控成骨细胞分化和骨的形成。
3.
Objective: To study the regulatory mechanism of PI3K signal pathway on osteoblast differentiation in pre-osteoblast MC3T3-E1.
方法 :首先通过Western印迹试验检测到PI3K信号通路参与成骨细胞分化的调控。
6) osteoblastic differentiation
成骨细胞分化
1.
Phytoestrogen Genistein induces osteoblastic differentiation of mouse bone marrow-derived mesenchymal stem cells through p38 MAPK;
植物雌激素金雀异黄酮通过p38MAPK通路促进骨髓间充质干细胞向成骨细胞分化
2.
The effects of Clomiphene on the proliferation and osteoblastic differentiation of mouse bone marrow-derived mesenchymal stem cells;
克罗米酚对骨髓间质干细胞增殖和向成骨细胞分化的影响
3.
To investigate the mechanisms of the inhibition of osteoblastic differentiation by dexamethasone (DEX), the effects of different doses of DEX on the activity of alkaline phosphatase (ALP), the synthesis of osteocalcin (OC) and the expression of colaggen type Ⅰ were observed in the cultured rat osteoblasts.
为探讨地塞米松 (dexamethasone ,DEX)抑制成骨细胞分化的机制 ,观察了不同浓度DEX对体外培养大鼠成骨细胞的碱性磷酸酶活性、骨钙素 (osteocalcin ,OC)合成、Ⅰ型胶原蛋白表达的影响 ,并用RT PCR方法检测了成骨细胞中LIM矿化蛋白 1mRNA的表达量。
补充资料:成骨细胞
成骨细胞
成骨细胞是骨的形成、骨骼发育与生长的重要细胞,其体积较大,呈立方形或矮柱状,胞浆较丰富,呈强嗜碱性。核大而圆,常位于胞体的一侧,核仁清晰可见。成骨细胞内富于核糖核酸,PAS染色呈阳性反应;碱性磷酸酶染色呈强阳性。成骨细胞可向其周围生生胶原纤维及基质,在未钙化前称为类骨质。类骨质的微纤维间彼此侧向融合,骨盐结晶逐渐沉积,最后类骨质区完全骨质化。成骨细胞在分泌类骨质的过程中逐渐被埋于其中并转变成骨细胞。成骨细胞还能形成基质小泡,其内含有大量的碱性磷酸酶、类脂及小的钙盐结晶体。基质小泡破裂后,碱性磷酸酶能使局部磷酸含量增高。磷脂与钙有很强的亲和力,可使钙盐结晶成为钙化核心,并使钙化范围逐渐扩大,从而导致类骨质的迅速钙化。
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参考词条