1) p38 mitogen-activated protein kinase
p38丝裂素活化蛋白激酶
1.
Expression and role of p38 mitogen-activated protein kinase in hyperoxia-induced lung injury juvenile rat model
p38丝裂素活化蛋白激酶在幼鼠高氧肺损伤模型中的表达及作用
2.
Objective To investigate the role of p38 mitogen-activated protein kinase(p38MAPK) pathway in the proliferation of SHR vascular smooth muscle cells(VSMC) induced by angiotensin Ⅱ(Ang Ⅱ) and platelet-derived growth factor-BB(PDGF-BB).
目的研究p38丝裂素活化蛋白激酶(p38MAPK)信号传导通路在血管紧张素Ⅱ(AngⅡ)与血小板源性生长因子-BB(PDGF-BB)诱导的自发性高血压大鼠(SHR)血管平滑肌细胞(VSMC)增殖中的作用。
3.
Objective To investigate the expression and significance of p38 mitogen-activated protein kinase (p38MAPK) in hyperoxia-induced lung injury of new-born rats.
目的探讨p38丝裂素活化蛋白激酶(p38mitogen-activatedproteinkinase,p38MAPK)在新生鼠高氧肺损伤中的表达及意义。
2) p38 mitogen-activated protein kinases
p38丝裂素活化蛋白激酶
1.
The signal pathway of p38 mitogen-activated protein kinases is the important to regulate the cell proliferation and differentiation under stress in many kinds of cells.
p38丝裂素活化蛋白激酶信号途径是多种细胞在应激条件下调节细胞增殖分化的重要信号通路，参与多种肾脏病理生理过程。
3) p38MAPK
丝裂素活化蛋白激酶p38
1.
OBJECTIVE ①To investigate the role of P38MAPK, iNOS, COX-2 and mitochondrial K+ATP channel, and explore the association among them in the late phase of ischemic preconditioning (IPC) in neonatal rat cardiomyocytes.
目的：（1）在大鼠心肌细胞缺氧预处理（ischemic preconditioning，IPC）晚期保护作用模型上，探讨丝裂素活化蛋白激酶P38（P38MAPK）、诱生型一氧化氮合成酶（iNOS）、环氧化酶-2（COX-2）和线粒体K+ATP通道的作用及相互关系。
4) P38MAPK
P38丝裂素活化蛋白激酶
1.
Divided the 80 rats into 10 groups randomly , as the group of nomal control, 1d after injury, 7d after injury, 14d after injury, control with SB203580 (A special inhibitor of P38MAPK), 1d 1d after injury with SB203580, 7d afte
本研究第一部分将以大鼠为研究对象,通过研究颅脑损伤后大鼠的受损脑组织与其周围脑组织中胶质纤维酸性蛋白和P38丝裂素活化蛋白激酶的表达情况,找到在脑外伤后血清胶质纤维酸性蛋白的变化规律以及表达上调的主要途径;本研究第二部分研究对象为人脑,通过检测脑外伤病人外周血中胶质纤维酸性蛋白浓度变化和检测手术患者脑组织中上述蛋白的表达水平高低,验证外周血血清浓度是否与脑组织蛋白表达水平相一致,并验证其在脑外伤患者诊断及预后判断上的敏感性和特异性,最终揭示该类神经标志物在对脑外伤患者诊断及预后判断上的意义。
5) P38MAPK
P38丝裂原活化蛋白激酶
1.
Expression of activated P38MAPK in retina of rat after crushing injury;
大鼠视神经损伤视网膜内P38丝裂原活化蛋白激酶活性的表达
2.
Changes of phosphorylated p38MAPK in the murine model of traumatic hemorrhagic shock with endotoxin;
大鼠创伤失血性休克复合内毒素打击模型中p38丝裂原活化蛋白激酶磷酸化水平的改变
3.
Objective:To explore the dynamic expression of P-selectin,MCP-1,NF-κB and p38MAPK in the renal tubules of diabetic rats and to investigate their mutual relationship and roles in the pathogenesis of diabetic nephropathy.
目的:观察糖尿病大鼠肾小管p38丝裂原活化蛋白激酶(p38MAPK)、NF-κB、I-κB、P选择素和MCP-1表达的动态变化,探讨相互间关系及在糖尿病性肾病(DN)发生发展中的作用。
6) p38 mitogen-activated protein kinase
p38丝裂原活化蛋白激酶
1.
Influence of sodium selenite on expression of p38 mitogen-activated protein kinase and peroxisome proliferator-activated receptor γ in rat mesangial cells line HBZY-1;
亚硒酸钠对大鼠肾小球系膜细胞表达p38丝裂原活化蛋白激酶和过氧化物酶体增殖物激活受体γ的影响
2.
Activation of p38 mitogen-activated protein kinase in spinal cord contributes to chronic constriction injury-induced neuropathic pain;
脊髓p38丝裂原活化蛋白激酶激活参与坐骨神经压迫性损伤所致神经病理性痛(英文)
3.
Expression of phosphorylating-p38 mitogen-activated protein kinase of kidney in rats with diabetes mellitus and its significance;
糖尿病大鼠肾脏组织中磷酸化p38丝裂原活化蛋白激酶的表达特征及意义
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