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1)  Hepatocyte apoptosis
肝细胞凋亡
1.
Relationship between hepatocyte apoptosis and the expression of Fas and Caspase-3 in fulminant hepatic failure;
暴发性肝衰竭中Fas及caspase-3与肝细胞凋亡的关系
2.
Relationship between the expressions of Bcl-2 protein and caspase-3 gene and hepatocyte apoptosis in fulminant hepatic failure;
Bcl-2蛋白及caspase-3基因表达与暴发性肝衰竭肝细胞凋亡关系的研究
3.
Effect of Rougan yixian decoction on hepatocyte apoptosis of experimental rat with hepatic fibrosis;
柔肝抑纤饮对实验性肝纤维化大鼠肝细胞凋亡的影响
2)  Hepatocellular apoptosis
肝细胞凋亡
1.
Methods:The models of hepatic fibrosis were made in rats by CCl_4,then,investigated the effect of EGB on the biochemical indices such as hepatic function and the expression of activin A and hepatocellular apoptosis.
方法:采用CCl4腹腔注射制造大鼠肝纤维化模型,观察EGB对肝纤维化大鼠肝功能生化指标、肝脏HE染色、Activin A(激活素A)表达及肝细胞凋亡的影响。
2.
To study the effects of “Fuzheng Huayu Decoction” on hepatocellular apoptosis in rats with DMN liver fibrosis, fifty-two rats were modeled to be liver fibrosis by 0.
结果:扶正化瘀方组大鼠死亡率、腹水发生率较模型组明显降低,肝功能好转;肝组织Hyp含量以及肝组织胶原分期下降,纤维化程度减轻;肝组织α- SMA表达明显降低,HSC凋亡增多,肝细胞凋亡减少,与模型组相比均有显著性差异。
3.
Objective: To probe the alterations of serum hyaluronic acid、hepatocellular apoptosis and apoptosis-regulating gene expression、regular liver function in rats with carbon tetrachloride-induced liver cirrhosis,the relationship between these indexes and liver reserve function after partial hepatectomy are also studied.
目的:通过测定大鼠肝硬化发展过程中及不同肝切量血清透明质酸、肝细胞凋亡及其调控基因表达的变化,与常规肝功能测定结果比较,了解上述指标与肝储备功能的关系。
3)  hepatic apoptosis
肝细胞凋亡
1.
Effect of reactive oxygen species in inducing hepatic apoptosis in rats with obstructive jaundice;
活性氧在梗阻性黄疸大鼠肝细胞凋亡中的作用研究
2.
Objective: To study the relation of TNF and hepatic apoptosis,and the effect of glucocorticoid(GC) on them in order to know the machnism of descrease of liver function and of interference of GC in sepatic rat.
各组均测定肝组织TNF-α和Bcl-2蛋白表达及肝细胞凋亡的情况,同时测定肝脏功能的变化。
3.
Objective: To study the relation of TNF and hepatic apoptosis, and the effect of GC on them in order to know the machnism of descrease of liver function and of interference of GC in sepatic rat.
目的:探讨脓毒血症时TNF-α与肝细胞凋亡的关系以及糖皮质激素对TNF-α和肝细胞凋亡的影响,了解脓毒血症时肝脏功能降低的机制及糖皮质激素的作用机制。
4)  Liver apoptosis
肝细胞凋亡
1.
Serum and liver tissure TNF α protein levels and liver apoptosis were measured at various intervals.
目的:探讨脓毒症大鼠肿瘤坏死因子a(TNF a)与肝细胞凋亡的关系以及对肝功能的影响。
2.
This research tries to study the connection between liver apoptosis and proliferation.
目的:揭示"高住低练"中肝细胞凋亡和增殖的情况及之间的关系。
3.
In conclusion,Bax、bcl-2 and HIF-1α gene participates to adjust liver apoptosis.
目的:探讨"高住低练"肝细胞凋亡调控基因,凋亡调控基因与HIF-1α之间关系。
5)  liver cell apoptosis
肝细胞凋亡
1.
Objective:To investigate the effect of Notoginseng saponin(NS)Rg_1 and Rb_1 on liver cell apoptosis and its related gene expression in acute liver damage.
目的:探讨三七皂甙对急性肝损害肝细胞凋亡及凋亡相关基因表达的影响。
2.
and compare protective liver action of north Chaihu and spring Chaihu on blood Biochemical indexes,the content of hepatic tissue collagen protein and liver cell apoptosis.
方法:采用二甲基亚硝胺(DMN)致大鼠慢性肝纤维化,从血液生化学、肝组织胶原蛋白含量、肝细胞凋亡比较春柴胡及北柴胡的保肝作用。
6)  Hepatoma cell apoptosis
肝癌细胞凋亡
补充资料:细胞凋亡
分子式:
CAS号:

性质:是细胞的一种不同于坏死的死亡方式,是由基因控制的细胞自我消亡过程,是一连串精确的生化变化的结果,不像坏死是意外事件使细胞受损伤的消极结果,其发生为机体维持衡态所需,因而有积极的生物学意义。细胞凋谢开始时,染色质凝集、分块,位于核膜上,细胞质凝缩,核及细胞的外形都有卷曲,几分钟后,核断裂,细胞表面有柄状突起,最后产生有膜包裹的细胞凋谢体,随即被周围的细胞所吞噬。这与坏死细胞完全不同,后者是不成形的染色质块,膨胀的细胞器,以及混浊的线粒体。细胞凋谢的另一特征是可能有新的蛋白质合成,可能是为启动细胞凋谢所需。程序化细胞死亡(programmed cell death;PCD)概念与细胞凋亡起于相同时期,常被认为有相关或甚至等同的意义。但是,尽管两者都不同于细胞坏死,即不伴有发炎和细胞崩溃及内含物的释放,都是由基因指导的细胞自我消亡,具有明确的生物学功能。但二者不能等同起来。PCD的细胞死亡是按照一定程序发生的变化。也有核固缩和胞质缩合等细胞凋亡现象。

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