1) kidney injury molecule-1
肾损伤分子1
1.
Objective To explore the relationship between the changes of urinary β2-microglobin (β2-MG), N-acetyl-beta-D-glucosaminidase (NAG) and kidney injury molecule-1 (KIM-1) in patients with contrast agent-induced nephropathy (CIN) by analyzing the level of urinary β2-MG, NAG and KIM-1.
目的通过检测造影剂相关性肾病患者尿液中β2微球蛋白(β2-MG)、N-乙酰-β-D-氨基葡萄糖苷酶(NAG)及肾损伤分子1(KIM-1)的水平,了解β2-MG、NAG及KIM-1在造影剂相关性肾病患者中的改变及其与肾功能之间的关系。
4) kidney injury molecule 1
肾损伤因子
5) Molecular damage
分子损伤
6) renal damage
肾损伤
1.
Determination of urine retinol binding protein and its clinical significance in patients with the early renal damage of diabetes;
糖尿病早期肾损伤患者尿视黄醇结合蛋白检测的临床意义
2.
Relationship between the changes of β EP\,β\-2 MG s concentrations in serum after asphyxia neonate and hypoxia cerebral damage and renal damage;
窒息新生儿血浆β-EP、β2-MG值变化与脑、肾损伤的关系
3.
Objective To evaluate if urinary proteins might be considered as a sensitive marker in diagnosing initial renal damage by detecting urinary proteins,and serum parameter of renal function in patients with multiple myeloma (MM).
结论:尿蛋白比其他生化指标能更好地识别早期阶段的肾损伤,是MM患者肾损伤灵敏的诊断指标。
补充资料:分子损伤(molecularLesion)
分子损伤(molecularLesion)
辐射造成生物大分子结构与功能的破坏,如放射引起的DNA的碱基损伤、糖基和氢键的破坏、单链或双链的断裂;DNA的合成受抑;DNA之间和DNA与蛋白质之间的交联被破坏等。就蛋白质和酶而言,放射可引起结构松散仍至分子断裂、蛋白质分子之间的交联及酶的失活等。放射可引起染色体畸变,小至基因上个别碱基的变化,大者可导致染色体大片段缺失、交换、颠倒、环和微核的形成等。
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