Establishment of murine model of haploidentical peripheral blood transplantation;

24 patients with various hematologic malignancies recieved PBSCT/BMT from their HLA matched or unrelated donors and haploidentical siblings in April-December 2007.

Clinical study on haploid HLA-haploidentical hematopoietic stem cell transplantation for treatment of malignant hematological disease

To explore the occurrence patterns of neurological complications following haploidentical bone marrow transplantation, a series of clinical data as the onset time, etiology, choices of therapies and prognosis in 10 patients with neurological disorders were summarized.

To explore the occurrence patterns of pulmonary complications at different stages in haploidentical bone marrow transplantation, a series of clinical data as the onset time, etiology, management choices and prognosis in 18 patients with pulmonary disorders were summarized.

This study was purpused to analyze the characteristics of T cell receptor repertoire in target organs of murine graft-versus-host after haploidentical bone marrow transplantation(hiBMT) and the molecular characteristics of complementarity determining region3 (CDR3) repertoires of monoclonal T cell in liver, skin and ileum in murine after hiBMT.

The aim of this study was to evaluate the impact of donor killer cell immunoglobulin-like receptor(KIR)and recipient HLA genotypes on outcome following haploidentical hematopoietic stem cell transplantation(HSCT).

To investigate the characteristics and significance of reconstitution of peripheral blood plasmacytoid dendritic cell (PDC) precursors after allogeneic human leukocyte antigen mismatched/ haploidentical hematopoietic stem cell transplantation, and its relationship with chronic graft versus host disease(cGVHD)and relapse, 19 patients with leukemia were enrolled for this study.