1) transforming growth factor-β1
转化生长因子β1
1.
Effect of Bushen Tiaojing recipe on expressions of transforming growth factor-β1 and its receptor in the ovary of androgen-induced sterile rats;
补肾调经方对雄激素致无排卵大鼠卵巢转化生长因子β1及其受体表达的影响
2.
Effect of valsartan on the expression of transforming growth factor-β1 and connective tissue growth factor in renal tubular epithelial cells of diabetic rat;
缬沙坦对糖尿病大鼠肾小管上皮细胞转化生长因子β1与结缔组织生长因子表达的影响
3.
Tazarotene inhibits proliferation of keratinocyte in vitro and enhances secretion of transforming growth factor-β1;
他扎罗汀对角质形成细胞体外增殖及分泌转化生长因子β1的影响
2) TGF-β1
转化生长因子β1
1.
The dynamic expression and content study of TGF-β1 and smad2/3、4 in the kidneys of diabetic rats;
转化生长因子β1及Smad2/3、4在糖尿病肾脏的动态表达及意义研究
2.
THE EXPRESSIONS AND SIGNIFICANCE OF TGF-β1,SMAD4 AND BAX PROTEIN IN THE DEVELOPMENT OF RAT EMBRYONIC HEART;
转化生长因子β1及Smad4、Bax蛋白在大鼠胚胎心脏发育中的表达及意义
3.
Tanshinone inhibits lysophosphatidic acid-induced cardiac fibroblast proliferation and TGF-β1 production in neonate rats;
丹参酮ⅡA对溶血磷脂酸致新生大鼠心脏成纤维细胞增殖及分泌转化生长因子β1的影响
3) transforming growth factor β1
转化生长因子β1
1.
The function of transforming growth factor β1 in myocardial protection and remodeling from ischemia-reperfusion injury;
转化生长因子β1在心肌缺氧缺血再灌注损伤修复及心肌重塑中的作用
2.
The mechanism of growth inhibition by transforming growth factor β1 (TGF-β1) on esophageal carcinoma cell in vitro;
转化生长因子β1抑制食管癌细胞的生长
3.
Influence of Yishenkang(益肾康) on transforming growth factor β1 expression in diabetic rats;
益肾康对糖尿病大鼠转化生长因子β1表达的影响
4) Transforming growth factorβ1
转化生长因子β1
1.
HPMC was cultured for 24 hrs in SKOV3-CM or SKOV3-CM with anti-transforming growth factorβ1(TGF-β1)neutralizing anti.
以SKOV3-CM或SKOV3-CM加转化生长因子β1(TGF-β1)中和抗体培育HPMC24h,检测其VEGF基因及蛋白表达的变化。
2.
Objective To examine the expression of vascular endothelial growth factor(VEGF)and its receptors(VEGFR1, VEGFR2)in transdifferentiated human proximal tubular epithelial(HK-2)cell induced by transforming growth factorβ1(TGFβ1).
目的探讨转化生长因子β1(TGFβ1)诱导人肾小管上皮细胞(HK-2)转分化过程中,血管内皮细胞生长因子(VEGF)及其受体表达的变化。
3.
Objective: To investigate the effect of high glucose on renal tubular Epithelial-Mesenchymal transition and evaluate the relationship between high glucose and transforming growth factorβ1.
目的:通过观察高糖对肾小管上皮细胞转分化(Epithelial-Mesenchymal Transition,EMT)的作用及其与转化生长因子β1(Transforming Growth Factorβ1,TGF-β1)的关系,探讨糖尿病肾病小管间质纤维化的发病机制。
5) transforming growth factor beta 1
转化生长因子β1
1.
The expression of transforming growth factor beta 1 in rat alveolar bone during orthodontic tooth movement;
大鼠正畸牙移动过程中转化生长因子β1在牙槽骨中的表达
2.
Transforming growth factor beta 1(TGF β 1) is cytokine which have many kinds of biological functions such as .
转化生长因子β1(TGF β1)是一种具有调节细胞生长、死亡或凋亡、细胞分化和细胞外基质合成等多种生物学功能的细胞因子,在肝脏细胞外基质的合成、沉积及降解的过程中起着至关重要的作用,与肝纤维化的发生机制有着密切的关系。
6) transforming growth factor-beta1
转化生长因子β1
1.
Interventional effects of emodin on transforming growth factor-beta1/integrin-linked kinase signal way in interleukin-1β-induced transdifferen-tiation of rat tubular epithelial-myofibroblasts
转化生长因子β1/整合素连接激酶信号通路在大鼠肾小管上皮细胞转分化中的作用及大黄素对其的干预效应
2.
Intracellular signal molecules, such as transforming growth factor-beta1 (TGF-beta1), Smad2 and phospho-Smad2 (p-Smad2) protein expression were determined by Western blot.
方法:体外分离培养乳鼠心肌细胞,用血管紧张素Ⅱ(AngⅡ)刺激产生肥大的心肌细胞,加入不同浓度的EPO对肥大心肌细胞进行干预,以细胞表面积和心钠素(ANF)mRNA表达作为细胞肥大的观察指标,采用Western blot方法检测细胞内信号分子转化生长因子β1(TGF-β1)、Smad2及p-Smad2蛋白表达。
补充资料:转化生长因子
分子式:
CAS号:
性质:是瘤细胞在生长过程中分泌的一组多肽类物质,因此可从瘤细胞株的培养液中提取它,也可从实体瘤组织中直接提取。TGF能促使瘤细胞自身迅速生长,因为它能与表皮生长因子(EGF)竞争受体,也就是说,肿瘤细胞本身具有结合这类多肽的受体。这就形成了一个阳性反馈系统,即瘤细胞分泌的TGF与瘤细胞自身受体结合,这种结合导致瘤细胞无法控制生长。TGF能使一些非转化指示细胞发生表型转化,生长接触抑制消失,导致在软琼脂上形成集落。TGF分子量6~25kD,依其与EGF竞争膜细胞受体结合点的能力不同及使正常指示细胞表型转化的程度不一,可分为三类:α-TGF, β-TGF及γ-TGF。
CAS号:
性质:是瘤细胞在生长过程中分泌的一组多肽类物质,因此可从瘤细胞株的培养液中提取它,也可从实体瘤组织中直接提取。TGF能促使瘤细胞自身迅速生长,因为它能与表皮生长因子(EGF)竞争受体,也就是说,肿瘤细胞本身具有结合这类多肽的受体。这就形成了一个阳性反馈系统,即瘤细胞分泌的TGF与瘤细胞自身受体结合,这种结合导致瘤细胞无法控制生长。TGF能使一些非转化指示细胞发生表型转化,生长接触抑制消失,导致在软琼脂上形成集落。TGF分子量6~25kD,依其与EGF竞争膜细胞受体结合点的能力不同及使正常指示细胞表型转化的程度不一,可分为三类:α-TGF, β-TGF及γ-TGF。
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参考词条