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1)  antitumor resistance
药物抵抗性
1.
Study on relationship between oxaliplatin antitumor resistance and ERCC1mRNA level in colorectal carcinoma cell lines;
目的分析草酸铂处理前后ERCC1 mRNA水平的变化,探讨肠癌细胞中ERCC1表达与草酸铂药物抵抗性的关联。
2)  drug resistance
药物抵抗
1.
While whether acquired drug resistance to anti-angiogenic therapies might be a feature of the TEC has not yet been reported.
目前,sorafenib等抗血管生成药物在肝癌的治疗上取得了进展,可延长患者生存期,但其疗效并不持久,通常几个月后即出现药物抵抗,肿瘤又重新生长,而其耐药机制尚不明了。
3)  resistance to chemotherapeutics
化疗药物抵抗
1.
Objective To detect the change of mutant P53 protein in cervical cancer before and after arterial interventional chemotherapy and to investigate the relationship between the protein and resistance to chemotherapeutics , therapeutic effect of arterial interventional chemotherapy.
目的 检测宫颈癌组织中突变型P53蛋白在动脉介入化疗前后的变化,探讨其与宫颈癌组织化疗药物抵抗以及动脉介入化疗疗效的关系。
4)  drug resistance
药物抗性
5)  drug resistance
药物抗药性
1.
Since uncertain relationship between mutation patterns and drug resistance is still unknown,consequently,we are interested in using multi-dimensional Bayesian classifier and causal polytree to learn those causalities underline HIV mutation patterns,furthered with how those relationships influence HIV drug resistance.
研究表明,艾滋病病毒的变异复杂,不断进化的突变类型对现有的任何药物都能产生抗药性,并且变异类型与HIV药物抗药性之间存在不确定性关系。
6)  drug antitumor
药物抗癌性
补充资料:放射性碘标记的放射性药物
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CAS号:

性质: 131I是最早用于临床的放射性核素之一。临床上常用的碘标放射性药物有:(1)Nal31I,用于甲状腺显像和甲亢治疗;(2)心肌显像用131I(123I)-CO-长链脂肪酸;(3)脑功能显像用123I(131I)-IMP(N-异丙基对碘安非他命,N-isopropyl-p-iodoamphetamine),123I(131I)-HIPDM[N,N,N′-trimethyl-N′-(2-hydroxy-3-methyl-5-iodobenzyl)-1,3-propanediamine];(4)受体显像用123I(131I)标记变体配体,如D1,D2,乙酰胆碱,安定类受体显像剂;(5)用于放射免疫显像和治疗的131I标记抗肿病抗体;(6)肾上腺显像剂131I-6-碘胆固醇、131I-间-碘苄胍等。

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