1) amyloid precursor protein
淀粉样蛋白前体
1.
Estrogen inhibition on the expression of amyloid precursor protein C-terminal in ovariectomized female rat hippocampus and cortex;
雌激素抑制淀粉样蛋白前体羧基端片段在雌性去势大鼠海马和脑皮质的表达
2.
Aim:To investigate the expressions of amyloid precursor protein(APP) and β-tubulin in plasma of patients with Alzheimer's disease(AD) or vascular dementia(VD),and the diagnostic value of changes of APP and β-tubulin for AD.
目的:对阿尔茨海默病(Alzheimer s disease,AD)与血管性痴呆(vascular dementia,VD)血浆β-微管蛋白与淀粉样蛋白前体(APP)进行定量分析,分析这些指标的变化是否可以为临床诊断阿尔茨海默病提供生物学方面的帮助。
3.
Methods DHPLC and DNA sequencing were used to examine the amyloid precursor protein and presenilin 1(PS1) gene of a 130 member family and a 50 member control group.
方法 应用 DHPLC方法及 DNA直接测序技术 ,对一个有 1 3 0人的AD大家系和 5 0名正常对照者进行了淀粉样蛋白前体 (amyloid precursor protein,APP)基因、早老素 1 (prese-nilin1 ,PS1 )基因的突变位点检测。
2) amyloid protein precursor
淀粉样蛋白前体
1.
Objective To investigate the pathogenesis of Alzheimer disease and study the enzymolysis of amyloid protein precursor(APP) and construct the recombinant eukaryotic expression plasmid containing APP Flemish mutation and yellow fluorescence sequence.
目的探讨阿尔茨海默病(Alzheimer disease)的发病机制,研究淀粉样蛋白前体(amyloid protein precursor,APP)酶解过程,构建含有APP Flemish突变的荧光真核表达系统。
3) Amyloid precursor protein
淀粉样前体蛋白
1.
Observation of amyloid precursor protein cleavage and Aβ generation in living cells by using multiphoton laser scanning microscopy;
多光子激光扫描成像技术对活细胞内淀粉样前体蛋白裂解和β-淀粉样蛋白生成的观察(英文)
2.
Expression of amyloid precursor protein in hippocampi of senescence accelerated mice prone 8;
淀粉样前体蛋白在快速老化痴呆小鼠P8海马中表达的免疫组化学研究
3.
Estrogen attenuates over-expression of amyloid precursor protein messenger RNA and inhibits congophilic Aβ in prefrontal cortex and hippocampus induced by hypercholesterolemia in ovariectomy rabbits
雌激素减少去卵巢兔高胆固醇诱导的淀粉样前体蛋白信使RNA过表达并抑制前额叶皮层Aβ表达(英文)
4) β-amyloid precursor protein
淀粉样前体蛋白
1.
Objective To investigate the expressions of β-amyloid precursor protein (APP) and β-amyloid protein (Aβ) in the brain of diabetic rats,and to explore the mechanism of glucose metabolic disorder in Alzheimer s disease.
目的观察糖尿病大鼠脑组织β-淀粉样蛋白(Aβ)、β-淀粉样前体蛋白(APP)表达,探讨糖尿病糖代谢异常在阿尔茨海默病中的作用机制。
5) APP
淀粉样前体蛋白
1.
10 days later,the morphological changes of neurons in hippocampus were observed by HE staining and electronmicroscope respectively,amyloid β-protein precursor(APP) gene expression in hippocampus was measured with in situ hybridization,and the product of amyloid β-protein(Aβ) was determined by immunohistochemistry st.
10 d后,利用苏木素-伊红(hematoxylin and eosin,HE)染色、电镜技术、原位杂交、免疫组化染色等方法,观察大鼠海马神经元、淀粉样前体蛋白(β-amyloid protein precursor,APP)基因表达水平及β-淀粉样蛋白(β-amyloid protein,Aβ)含量的变化。
2.
Amyloid precursor protein (APP) has been known to act as an important protein during the occurrence of Alzheimer s disease (AD).
淀粉样前体蛋白 (APP)是阿尔茨海默氏病 (AD)发病过程中有重要作用的蛋白 。
6) β-amyloid precursor protein
β-淀粉样蛋白前体蛋白
1.
Advances in understanding the β-amyloid precursor protein intracellular domain;
β-淀粉样蛋白前体蛋白胞内结构域(AICD)研究进展
补充资料：核蛋白体、核糖核蛋白体
分子式：
CAS号：
性质：又称核蛋白体、核糖核蛋白体。一种亚细胞核蛋白颗粒，由大约等量的核糖核酸(RNA，35％～55％)和蛋白质(45％～65％)组成。是细胞内蛋白质合成的场所。多个核糖体可以联接成串，形成多聚核糖体。每个核糖核蛋白体在外形上近似球形，直径约20nm。由两个不同的亚基组成(大亚基和小亚基)，通过镁离子和其他键非共价键地结合在一起。已证实有四类核糖核蛋白体：细菌、植物、动物和线粒体，它们以其单体的、亚单位的和核糖核蛋白体RNA的沉降系数相区别。核蛋白体有两个结合转移RNA的部位(A部位和P部位)，并能附上信使RNA，(Rb)。
CAS号：
性质：又称核蛋白体、核糖核蛋白体。一种亚细胞核蛋白颗粒，由大约等量的核糖核酸(RNA，35％～55％)和蛋白质(45％～65％)组成。是细胞内蛋白质合成的场所。多个核糖体可以联接成串，形成多聚核糖体。每个核糖核蛋白体在外形上近似球形，直径约20nm。由两个不同的亚基组成(大亚基和小亚基)，通过镁离子和其他键非共价键地结合在一起。已证实有四类核糖核蛋白体：细菌、植物、动物和线粒体，它们以其单体的、亚单位的和核糖核蛋白体RNA的沉降系数相区别。核蛋白体有两个结合转移RNA的部位(A部位和P部位)，并能附上信使RNA，(Rb)。
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参考词条