2) O-alkylation
O-烷基化
1.
Ten open chain analogues with nitrogen or carbon as central atom (1a-e, 2a-e) were synthesized through O-alkylation of trithanoiamme, pentaerythritol and 4-hydroxy-antipyrine and S-alkylation of 2-mercaptobenzimidazole and 2-mercaptobenzothiazole with pentaerythrityltetrabromide.
通过三乙醇胺、季戊四醇及4-羟基安替比林的O-烷基化和用季戊四溴对2-巯基苯并咪唑、2-巯基苯并噻唑的S-烷基化方法。
2.
The O-alkylation of 2,5-dimethylphenol with 1,3-dihalogen- propane and some monohalogen carboxylic esters are studied.
研究了2,5-二甲苯酚与1,3-二卤代丙烷及一卤代羧酸酯的O-烷基化反应。
3) O-dealkylation
O-去烷基化
1.
The N-, O-dealkylation metabolism of verapamil and naproxen via microbial transformation was studied in this paper, and the similarities and differences between fungi and humans were compared.
本文以维拉帕米和萘普生两种药物为代表，探讨了微生物尤其是真菌在药物N-，O-去烷基化代谢研究中的应用，比较了真菌与人体在这两种药物代谢之间的异同，并制备了部分代谢物纯品；采用超速离心法制备了真菌微粒体，测定了其活性并研究了其对药物的转化能力，从亚细胞水平研究了真菌进行药物转化的机理；利用人体细胞色素P450酶的特异性底物及其相应的特异性化学抑制剂，探讨了真菌细胞内相关的药物转化酶与人体内药物代谢酶的异同。
4) N-alkyl-lactosylated-O
N-烷基乳糖基-O
1.
N-alkyl-lactosylated-O,N-carboxymethyl chitosan are prepared by carboxymethyl-chitosan with alkyldehyde and lactose.
通过羧甲基壳聚糖与醛和乳糖反应制得N-烷基乳糖基-O,N-羧甲基壳聚糖,并以戊二醛为交联剂制成水凝胶;以人血清蛋白作为模型药物,初步探讨了该水凝胶对蛋白类药物的释放规律。
5) 3 O alkyl glycerol
3-O-烷基甘油
6) O Butylchitosan
O-丁烷基壳聚糖
补充资料：(1R,S)-顺反式-2,2-二甲基-3-(2-甲基-1-丙烯基)环丙烷羧酸-[2,5-二氧-3-(2-丙炔基) ]-1-咪唑烷基甲基酯
分子式：C17H22N2O4
分子量：318.37
CAS号：72963-72-5
性质：密度0.979。闪点110°C。
分子量：318.37
CAS号：72963-72-5
性质：密度0.979。闪点110°C。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条