1) chlorpheniramine
[,klɔ:feni'ræmin]
氯苯那敏
1.
Simultaneous determination of ephedrine and chlorpheniramine in human plasma by a highly sensitive liquid chromatography-tandem mass spectrometric method;
高灵敏度LC/MS/MS法同时测定人血浆中麻黄碱和氯苯那敏
2.
Simultaneous determination of chlorpheniramine and caffeine concentrations in human plasma by liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry
液相色谱-大气压化学电离-串联质谱法同时测定人血浆中氯苯那敏和咖啡因的含量
3.
Electrochemical characterization of chlorpheniramine and its interaction with β-Cyclodextrins in Na 2HPO 4 buffer solutions with different pH values were studied with linear sweep voltammetry.
以氯苯那敏和 β$C环糊精为研究对象 ,利用电化学方法测定了它们相互作用形成超分子化合物的结合常数。
2) chlorphenamine
氯苯那敏
1.
Determination of phenylephrine and chlorphenamine in nasal drops by HPLC;
HPLC法同时测定去氧肾上腺素、氯苯那敏的含量
2.
In order to investigate the effect of dexamethasone,cyclosporin and chlorphenamine on basophils in vitro,we assessed activation marker on the surface of basophils stimulated by anti-IgE antibody.
目的在体外建立IgE介导的嗜碱粒细胞活化模型,通过加入不同药物浓度的地塞米松、环孢素和氯苯那敏,观察嗜碱粒细胞表面活化标记表达的变化,探讨药物对体外嗜碱粒细胞活化的作用。
3.
Objective To analyze the clinical features,correlation factors,prevention and cure of adverse drug reactions(ADR) caused by chlorphenamine.
目的探讨氯苯那敏致药品不良反应(ADR)的一般规律和特点。
3) dextrochlorpheniramine
右氯苯那敏
1.
Objective To develop LC-MS/MS method for the simultaneous determination of paracetamol and dextrochlorpheniramine in human plasma and to study the urinary excretions of the drugs.
目的建立高效液相色谱-串联质谱联用法同时测定人尿中对乙酰氨基酚和右氯苯那敏(解热镇痛药)浓度及其排泄。
4) chlorphenamine maleate
马来酸氯苯那敏
1.
Flow Injection Chemiluminescence Determination of Chlorphenamine Maleate;
流动注射化学发光测定马来酸氯苯那敏
2.
Simultaneous determination of guaiacol glyceryl ether, chlorphenamine maleate and methylephedrine hydrochloride in Keliting by HPLC;
用HPLC法同时测定可立停中的愈创木酚甘油醚、马来酸氯苯那敏和盐酸甲基麻黄碱
3.
Pharmacokinetics and bioavailability of paracetamol,amantadine hydrochloride and chlorphenamine maleate in paracetamol,amantadine hydrochloride,artificial cow-bezoar and chlorphenamine maleate granules in Chinese healthy volunteers by LC-MS/MS method;
LC-MS/MS法研究氨金黄敏颗粒中对乙酰氨基酚、盐酸金刚烷胺和马来酸氯苯那敏的人体药动学及相对生物利用度
5) chlorpheniramine maleate
马来酸氯苯那敏
1.
Preparation of 100 micron grade microcapsules of chlorpheniramine maleate for bitter taste masking;
流化床包衣法制备100μm级马来酸氯苯那敏掩味微囊
2.
Studies on preparation of chlorpheniramine maleate-resin complexes;
马来酸氯苯那敏药物树脂复合物制备工艺研究
3.
HPLC determination of chlorpheniramine maleate and ephedrine hydrochloride in Biyanling nasal drops;
HPLC法测定鼻炎灵滴鼻液中盐酸麻黄碱和马来酸氯苯那敏的含量
6) Chlorphenamine
马来酸氯苯那敏
1.
RP-HPLC determination of paracetamol, caffeine and chlorphenamine maleate in Compound Ganmaoling Tablets;
RP-HPLC测定复方感冒灵片中对乙酰氨基酚、咖啡因和马来酸氯苯那敏的含量
2.
A simple and rapid method for simultaneous determination of paracetamol, caffeine and chlorphenamine maleate in Suxiaoshangfeng capsule by capillary gas chromatography with nhexadecane as internal standard has been reported.
用５％Ｐｈ－Ｍｅ－Ｓｉｌｉｃｏｎｅ毛细管色谱柱，ＦＩＤ，二阶程序升温，以正十六烷作为内标物测定速效伤风胶囊中对乙酰氨基酚、咖啡因、马来酸氯苯那敏的含量。
3.
Methods Atificial Cow-bezoar was identified by TLC,and content of Chlorphenamine was determinde by HPLC.
方法采用薄层色谱法对处方中的人工牛黄进行鉴别;采用高效液相色谱法对马来酸氯苯那敏进行含量测定。
补充资料：氯苯那敏
分子式：C16H19ClN2
分子量：274.80
CAS号：132-22-9
性质：油状液体。沸点142℃（133Pa）。
制备方法：由2-对氯苄基吡啶经两步缩合而得。在干燥的反应锅内，加入氨钠、无水甲苯，加热至回流，将2-对氯苄基吡啶和溴代乙醛缩二乙醇同时滴入。加毕，回流反应8h。冷却静置，取甲苯液，固体物用少量水溶解后以甲苯提取。将提取液与甲苯液合并，水洗至中性，回收甲苯，得3-对氯苯-3-（2-吡啶基）-丙醛缩二乙醇。将其与DMF混匀加入反应锅，搅拌下加入甲酸与水的混合液。加热至110-120℃反应2h，150-160℃反应3h。冷却，减压回收DMF，加热水稀释，用碱液调至pH14。然后用甲苯提取，用水洗提取液至中性，回收甲苯后减压蒸馏，收集150-190℃馏分，得氯屈米通。
用途：抗组织胺药。与氯屈米通相类似，溴苯吡胺也中抗组织胺药。溴苯吡胺的生产方法也与氯屈米通相类似，只不过将起始原料用溴苯化合物代替。
分子量：274.80
CAS号：132-22-9
性质：油状液体。沸点142℃（133Pa）。
制备方法：由2-对氯苄基吡啶经两步缩合而得。在干燥的反应锅内，加入氨钠、无水甲苯，加热至回流，将2-对氯苄基吡啶和溴代乙醛缩二乙醇同时滴入。加毕，回流反应8h。冷却静置，取甲苯液，固体物用少量水溶解后以甲苯提取。将提取液与甲苯液合并，水洗至中性，回收甲苯，得3-对氯苯-3-（2-吡啶基）-丙醛缩二乙醇。将其与DMF混匀加入反应锅，搅拌下加入甲酸与水的混合液。加热至110-120℃反应2h，150-160℃反应3h。冷却，减压回收DMF，加热水稀释，用碱液调至pH14。然后用甲苯提取，用水洗提取液至中性，回收甲苯后减压蒸馏，收集150-190℃馏分，得氯屈米通。
用途：抗组织胺药。与氯屈米通相类似，溴苯吡胺也中抗组织胺药。溴苯吡胺的生产方法也与氯屈米通相类似，只不过将起始原料用溴苯化合物代替。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条