Separation of ibuprofen enantiomers by chiral extraction with hydrophobic tartaric esters;

Synthesis of L-Asp_6-Ibuprofen;

Composite microparticles of ibuprofen/lipid generated by supercritical fluids from their melts;

METHODS Liquid Ibuprofen Zinc was substituted Zinc oxide work as catalyst,and carried on the orthogonal experiment to optimized the technique design.

The initial strain,Trichosporon Lactis T,isolated from soil sample,having the capability of enantioselectively hydrolyzing S-isomer of racemic ibuprofen ethyl-ester into the corresponding S-ibuprofen,was implanted by 30KeV,1×10~(15) ions/cm~2～5×10~(15) ions/cm~2 low-energy N~+ for the purpose of obtaining mutants with high-efficiency hydrolyzing enzyme to produce active S-ibuprofen.

The S-ibuprofen molecularly imprinted polymers(MIPs) microspheres with diameter sizes of 3-6 μm have been prepared by a precipitation polymerization method using acrylamide(AM) as functional monomer and divinylbenzene(DVB) as cross-linker in a mixture solvent of toluene and acetonitrile.

Determination of Brufen in Brufen Troche by High Performance Ion Chromatography;

The research of application of brufen in acute lung injury patients;

A novel prodrug of brufen (4-isobutyl-α-methylphenylacetic acid) was designed and synthesized.

Gas Chromatographic Determination of Ibuprofen Tablets

Objective: Through improving technique, to solve sticking and picking of ibuprofen tablets in production.

The effect of sugarcoat on the determination of ibuprofen tablets by titration method are studied.