Chlorfenapyr, a product developed by American Cynamid Company, derived from dioxapyrrolomycin which metabolized from a Streptomyces fumanus strain, is a novel arylpyrrole insecticide and acaricide with high activity and broad spectrum.

Synthesis and anti-inflammatory and analgesic activities of 3-aryl-2-methyl-1-pyrrolo[1,2-a]pyrazinones;