In this paper,the chitosan-based advanced materials which general related to the drug delivery system reported since 2000 have been reviewed on the fabrication and application.

A novel pH-sensitive drug release system was fabricated by coating hydroxypropyl methylcellu-lose phthalate (HPMCP) on a drug-loaded SBA-15 tablet.

Chitosan is valuablely developed and applied in medical fields such as tissue engineering scaffold,gene carrier,membrane dialysis,surgical trauma coating material and drug release material for its physiological activity,antibacterial property and blood compatibility.

In this paper,the research of CPC as drug delivery system has been generally introduced in respects of its physicochemical properties and me.

AIM: To study a novel drug delivery system based on calcium phosphate cement (CPC) in vitro with sodium neproxen (SN) as a model drug.

Its structure, some physical and chemical nature, showed that ESO-lactide is a very good drug delivery carrier, but some troubles in physical-chemistry property aspects haven’t been solved in the past.

Release rates of the loaded avermectin varied in different dissolving media, and different concentrations of the same dissolving medium would cause different release speeds, which is very important in the study of sustained drug release.