Research on isolation and purification of total iridoid glycosides from herbal Lamiophlomis rotata;

The objective of the study is to optimize the process for extraction technology of total iridoid glycoside of Cape Jasmine Fruit.

In this thesis, we will study its aqueous extract s (HLRE) effects and mechanisms on hemorrhage, screen the effective composition, compare the toxicities of HLRE and Total Iridoid Glycoside (P_2), separate the HLRE to get the effective component and set up the standard of quality control (QC).

Effect of the Hematostatic Components Total Iridoid Glycosides of Habra Lamiophlomis Rotata on Rats Blood Conglomeration Parameters;

Purification of total iridoid glycosides and geniposide in Gardenia jasminoides with HPD450 macroporous resin;

Ultrastructural ObservatiOn on the Charges of Diabetes Mellitus Rat Renal After Treated with HXMTZG for Scanning Election Microscope;

Effect of HXMTZG on sICAM -1, TNF -α in serum of diabetic angiopathy rats induced by streptozotocin;

Impact of Fructus Corni Iridoid Glycosides on ACE-P of Rat Serum in Vascular Comlipcations of Diabetes;

At the same time, UV and HPLC methods were used to determine the content of total secoiridoids and gentiapicroside in wild Gentiana scabr.

Effects of cornus officinals iridoid glycoside on cellular model of alzheimer disease induced by protein phosphatase inhibitor okadaic acid;

(Scrophulariaceae),one new iridoid glycoside,7-O-acetylgardoside methyl ester(2)was isolated,together with twelve known compounds,gardoside methyl ester(1),verbascoside(3),leucosceptoside A(4),jionoside D(5),martynoside(6),2″-O-acetylmartynoside(7),uridine(8),adenosine(9),benzyl alcohol-O-β-D-xylopyranosyl-(1→2)-β-D-glucopyranoside(10),2-phenylethyl O-β-D-xylopyranosyl-(1→2)-β-D-glu.

Objective: To observe the change of nitric oxide(NO)and expression of nuclear factor-kappa B(NF-κΒ) in the cortex of cerebral infarction rat induced by photochemical reaction,and study the effect of extract from Cornus officinalis(whose main ingredient is iridoid glycoside) in the course of disease.