1) Williamson reaction
Williamson法
1.
Tetraethylene glycol dimethyl ether was synthesized by an improved Williamson reaction with tetraethylene glycol, methyl chloride and alkaline hydroxide at the suitable molar ratio ofn(C 8H 18 O 5)∶n(CH 3Cl)∶n(MOH)=1∶(2-3)∶(2-5).
以四甘醇 (C8H18O5)、氯甲烷 (CH3Cl)及固体碱性氢氧化物 (MOH)为原料 ,按n (C8H18O5)∶n (CH3Cl)∶n (MOH) =1∶( 2～ 3)∶( 2～ 5) ,采用Williamson法合成四甘醇双甲醚。
2) Williamson Reaction
Williamson反应
1.
Diethylene glycol butylmethyl ether(DGBME) was synthesized through Williamson Reaction with diethylene glycol mono-methyl ether(DEGME) and butyl bromide(n-C4H9Br) as starting materials at the atmosphere of N2,hydrate sodium as catalyst and benzene as water carrier,its synthetic condition was optimized by orthogonal experiment.
在氮气保护下,以二乙二醇单甲醚(C5H12O3,DEGME)和正溴丁烷为(n-C4H9Br)原料,氢氧化钠为催化剂,苯为带水剂,通过Williamson反应合成了二乙二醇甲基丁基醚(DGBME);用正交实验法对合成条件进行了优化,气相色谱法分析了产品中DGBME的含量,FT-IR和1HNMR法表征了产物结构。
2.
Diethylene gly- col butylmethyl ether (DGBME) was synthesized through the Williamson reaction between butyl bro- mide (n-C_4 H_9 Br) and CH_3 OCH_2 CH_2OCH_2 CH_2 ONa.
通过正溴丁烷与二乙二醇单甲醚钠的Williamson反应合成了二乙二醇甲基丁基醚(DGBME)。
3.
Williamson reaction is one important method to prepare unsymmetric ether.
Williamson反应是制备不对称醚类化合物的重要方法。
3) Williamson etherification
Williamson醚化
4) Williamson method
Williamson醚合成
1.
Through Williamson method, we have synthesized some hydroquinone ethyl ether chain 2HQ and 3HQ from simple materials.
用Williamson醚合成法,使用简易原料合成了氢醌乙醚链化合物2HQ和3HQ。
5) williamson alkylation
Williamson烷基化
6) Williamson's hypothesis
Williamson假说
补充资料：Williamson synthesis
分子式：
CAS号：
性质：卤代烷与醇钠、酚钠反应生成醚。可用于对称的和不对称的醚的合成。卤代烷的X活性顺序为I>Br>C1；R的活性顺序为叔烷基>仲烷基>伯烷基。卤代烷可用硫酸酯、对甲苯磺酸酯代替。
CAS号：
性质：卤代烷与醇钠、酚钠反应生成醚。可用于对称的和不对称的醚的合成。卤代烷的X活性顺序为I>Br>C1；R的活性顺序为叔烷基>仲烷基>伯烷基。卤代烷可用硫酸酯、对甲苯磺酸酯代替。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条