1) p or m-phenylene bispyrazolone carboxylic esters
对(间)苯撑双吡唑酮羧酸酯
2) 1-phenyl-3-carbethoxy-5-pyrazolone
1-苯基-3-羧酸乙酯-5-吡唑啉酮
1.
It condensed with phenyl hydrazine in the acid condition, and then cyclizated and acidified to prepare 1-phenyl-3-carbethoxy-5-pyrazolone.
以乙酸乙酯和草酸二乙酯为原料,经交叉Claisen酯缩合反应合成2-氧代丁二酸二乙酯钠盐,用此盐与苯肼在酸性条件下进行加成缩合反应制得苯腙,再经闭环、酸化可制得1-苯基-3-羧酸乙酯-5-吡唑啉酮。
3) 1-(benzol-4-sufonic acid)-5-pyrazolon-3-carbonicacid
1-对苯磺酸基-3-羧基-5-吡唑啉酮
4) imidazolonoxyphenoxycarboxylic ester
咪唑啉酮氧苯氧羧酸酯
1.
The imidazolonoxyphenoxycarboxylic esters(6a~6g) were synthesized by a new tandem aza Wittig reaction of vinyliminophosphorane 2, aromatic isocynate and substituted phenols.
研究了应用烯基膦亚胺与芳基异氰酸酯、取代酚的串联 aza-Wittig反应 ,来合成咪唑啉酮氧苯氧羧酸酯类化合物的新方法 。
5) poly(p-phenelene vinylene)carboxylic ester
聚羧酸对苯撑乙炔酯
1.
The five poly(p-phenelene vinylene)carboxylic ester were synthesized by Friedel-Crafts polymerization of phenylacetyl chloride to form poly(α-hydroxyl-p-phenyl-acetyl)and then esterificatoin with acyl chloride,and characterized by IR, 1H-NMR and ultraviolet-visible spectrum.
报道了新型可溶性聚羧酸对苯撑乙炔酯的合成方法。
6) 3,3'-tetramethylene-bis-(1-phenyl-5-pyrazolone-4-carboxylic ester)
3,3'-四亚甲基-双-(1-苯基-5-吡啶酮-4-羧酸酯)
补充资料:氰双吡酮
3-腈基-6-甲基-5-(4-吡啶基)-2(1H)-吡啶酮;6-Dihydro-2-methyl-6-oxo-(3,4′-bipyridine)-5-carbonitrile
分子式:C12H9N3O
分子量:211.22
CAS :78415-72-2
从二甲基甲酰胺-水或乙醇中结晶。白色结晶,微溶于水,在DMSO中的溶解度为20mg/ml,在乙醇中的溶解度3mg/ml。熔点》300℃。
用途:新型非苷类非儿茶酚胺类强心药,作用与氨吡酮相似,正性肌力作用强,约为氨力农的20~50倍,并有明显的扩张血管平滑肌的作用,能降低心脏负荷,还能极好地改善肾脏和肌肉供血。用于慢性心力衰竭及充血性心力衰竭等严重的心力衰竭和已发生洋地黄中毒的心力衰竭者。本品能明显改善心力衰竭者全身血流动力学各种参数,无血小板减少和低血压副作用.
说明:补充资料仅用于学习参考,请勿用于其它任何用途。
参考词条