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1)  sophoridine
槐定碱
1.
Study on preparation process of sophoridine microsphere;
槐定碱白蛋白微球制备工艺研究
2.
Simultaneous determination of contents of sophoridine,oxymatrine and oxysophocarpine in seed of Sophora alopecuroides by HPLC;
HPLC同时测定苦豆子中槐定碱、氧化槐果碱和氧化苦参碱的含量
3.
Determination of sophoridine,matrine and sophocarpine in Saphora alopecurodies injection by RP-HPLC;
RP-HPLC法测定苦豆子总碱注射液中槐定碱、苦参碱和槐果碱的含量
2)  sophocarpine [səufə'kɑ:pi:n]
槐定碱
1.
Objective:To make the rat model of epilepsy with sophocarpine, to observe the behavior and electroencephalograph in waking state of rats.
目的:建立槐定碱(sophojridine,SRI)诱导大鼠癫痫模型,同步观察槐定碱致痫大鼠行为和清醒脑电的变化,并探求细胞因子与癫痫发病之间的关系。
2.
Objective: To investigate the effect and explore the mechanism of protective role exerted by Total Alkaloids of Sophora Alopecuroides and three kinds of pharmacoalkaloids(Sophocarpine,Sophoridine,Oxymatrine) in mouse model with acute lung injury.
目的:研究苦豆子中提取的苦豆子总碱及氧化苦参碱、槐定碱、槐果碱对内毒素肺损伤小鼠模型的干预作用及其作用机制。
3.
Methods: After Kushen (Radix Sophorae Flavescentis) in this capsule was idetified the content of matrine and sophocarpine was detected by TLC.
方法 :采取TLC法对处方中苦参进行定性鉴别 ,并用TLC法测定其中苦参碱、槐定碱的含量。
3)  sophoridinol
槐定醇碱
1.
Conclusion:The structure of sophoridinol and isosophoridinol is reported for the first time.
结果:确证未知杂质为一对差向异构体,即槐定醇碱和异槐定醇碱,以1∶1比例形成共晶化合物。
4)  oxysophoridine
氧化槐定碱
1.
Effects of oxysophoridine on Glu and GABA immuno-reaction positive neurons in cortex and hippocampus of rats;
氧化槐定碱对大鼠皮层及海马谷氨酸及γ-氨基丁酸免疫阳性细胞的影响
2.
The analgesic action of oxysophoridine and its effect on the expression of PKCγ in central nervous system of mice
氧化槐定碱镇痛作用及其对小鼠中枢PKCγ表达的影响
5)  Sophoridine
盐酸槐定碱
1.
The initial application of Sophoridine combined with lipiodol in TACE for liver metastases caused by gastroenteric tumor;
盐酸槐定碱注射液联合超液化碘油在胃肠道肿瘤肝转移化疗栓塞中的初步应用研究
6)  isosophoridinol
异槐定醇碱
1.
Conclusion:The structure of sophoridinol and isosophoridinol is reported for the first time.
结果:确证未知杂质为一对差向异构体,即槐定醇碱和异槐定醇碱,以1∶1比例形成共晶化合物。
补充资料:槐定碱
分子式:
CAS号:

性质:又称槐树定,槐定。白色粗针状或大棱柱状结晶(由石油醚中),味苦,熔点108~110℃,旋光度[α]D-63.45°(c=0.9879,水)。易溶于水、甲醇、乙醇、四氯化碳等溶剂。植物来源有豆科植物苦豆草(Sophora alopecuroides L.),日本山豆根(guchresta japonica Benth.),苦参(Sophora flavescens Ait)的根等。具有抗肿瘤、抗心律失常、抗炎抑菌、抗胆碱、抗被动皮肤过敏及止痢作用,还具有体外抑精和免疫抑制作用。临床试用于治疗恶性葡萄胎和绒毛上皮癌,是一种高效低毒的抗癌生物碱。

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