Effect of antiplatelet drugs on the incidence of restenosis after percutaneous transluminal coronary angioplasty and in-stent implantation;

This article introduces the mechanism of currently available antiplatelet drugs as well as their practice guidelines and evidence from clinical trials.

Many clinical studies have confirmed that antiplatelet drugs act important roles to prevent and treat the cardiac disease,cerebrovascular disease and peripherial artery disease,such as aspirin,thienopyridine,GP Ⅱb/Ⅲa receptor antagonist,cilostazol and so on.

It is well recognized that antiplatelet agent is effective in the prevention and treatment of thrombosis.

Clopidogrel——a new antiplatelet agent;

Blood perfusion-independent neuroprotection induced by antiplatelet agents and its gender-difference;

Antiplatelet agents play an important role in the treatment of ACS.

Based on the pathophysiology of the coronary heart disease,especially acute coronary syndromes,The mechanisms,pharmacy and clinical appraisal of the antiplatelet agents were reviewed.

Platelet antagonists and anticoagulant is safe and effective based on conventional anti-ischemic therapy in the treatment of ACS and nursing care should be strengthened for these patients because anticoagulant and platelet antagonists may cause bleeding.

Study of Platelet Antagonists and Hypomolecular Heprin to Acute Non-ST Elevation Myocardial Infarction on the Basis of Evidence-based Nursing