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1)  mitomycin C
丝裂霉素C
1.
Preparation and physical properties of ferromagnetic mitomycin C-bearing microspheres;
丝裂霉素C铁磁性微球的制备及物理性质研究
2.
Influence on the postoperative recurrence site in bladder cancer treated with Mitomycin C during Surgery;
丝裂霉素C术中应用对膀胱癌术后复发部位的影响
3.
Treatment of pterygium with mitomycin C and triamcinolone combined stem cell transplantation;
丝裂霉素C、氟羟强的松龙联合干细胞移植治疗翼状胬肉疗效观察
2)  MMC
丝裂霉素C
1.
Transplantation of auto-corneal limbus stem cell combined with MMC treating recurrent pterygium;
自体角膜缘干细胞移植联合丝裂霉素C治疗复发性翼状胬肉
2.
A Clinical Study of MMC for Prevention Against Haze after LASEK;
丝裂霉素C防止LASEK术后角膜雾状混浊的临床研究
3.
Application of adjusting suture and MMC in the treatment of glaucoma by trabeculectomy and nursing care;
可调节缝线及丝裂霉素C在青光眼小梁切除术中的应用与护理
3)  Mitomycin-C
丝裂霉素C
1.
Effects of mitomycin-C on Haze formation after LASEK on patients with high myopia;
丝裂霉素C对高度近视患者LASEK术后Haze形成的影响
2.
Non-penetrating Trabecular Surgery with Mitomycin-C and Amniotic Membrane Implant Treat the Refractory Juvenile Open Angle Glaucoma;
非穿透小梁切除术联合丝裂霉素C及羊膜植入术治疗难治性青少年开角型青光眼
3.
Effects of Intravesical Instillation of Mitomycin-C Plus Hyaluronidase on The Prevention of Recurrence of Bladder Cancer;
丝裂霉素C加透明质酸酶膀胱灌注预防膀胱癌复发的疗效观察
4)  Mitomycin [英][,maitə'maisin]  [美][,maɪtə'maɪsɪn]
丝裂霉素C
1.
Effect of Mitomycin C on Treatment of Glaucoma by Trabeculacetomy;
丝裂霉素C在青光眼小梁切除术中的疗效
2.
Growth inhibition effect of mitomycin polybutylcyanoacrylate magnetic nanoparticles on L-02 cell;
丝裂霉素C聚氰基丙烯酸正丁酯磁性纳米球对肝细胞L-02的生长抑制作用
3.
Mitomycin C at 0.
目的:探讨丝裂霉素C和肝素用于小梁切除术的临床疗效。
5)  mitomycin C(MMC)
丝裂霉素C
1.
Application of retro-irrigation and Mitomycin C(MMC) in repair of canalicular laceration.;
逆行注水法及丝裂霉素C修复泪小管断裂
2.
Objective To investigate the effects of TNF-related apoptosis-inducing ligand(TRAIL) and mitomycin C(MMC) on the apoptosis of human prostatic cancer cell DU145.
目的研究肿瘤坏死因子相关的凋亡诱导配体(TRAIL)和丝裂霉素C(MMC)对前列腺癌细胞的杀伤作用及其协同作用。
3.
Objective:To prepare anti-tumor magnetic nanoparticles containing mitomycin C(MMC).
目的:以丝裂霉素C为药物模型,研究磁性纳米抗肿瘤药物的制备工艺及方法。
6)  mitomycin C
丝裂霉素-C
补充资料:丝裂霉素C
分子式:C15H18N4O5
分子量:334.33
CAS号:50-07-7

性质:蓝紫色有光泽的结晶。360℃以上分解。溶于水、甲醇、丙醇、乙酸丁酯和环已酮,微溶于苯、四氯化碳和醚,几乎不溶于石油醚。其水溶液对酸、碱均不稳定。

制备方法:用发酵方法生产。自放线菌(Strepto-myces caespitosus)培养液可提出丝裂霉素A、B、C。我国从自己分离的放线菌H2760菌株中提取,又称自力霉素,与国外报道的丝裂霉素C相同。

用途:该品抗瘤谱较广,用于胃癌、乳腺癌效果好。对肺癌、肝癌、恶性化淋巴瘤、何杰金氏病、网状细胞肉瘤、子宫癌、白血病、肠道癌和胰腺癌等均有一定疗效,但缓解期较短。与尿激酶合用可提高疗效,该品作用迅速,但治疗接线员数不高,毒性大。该品和博来霉素及其衍生物派来霉素都是破坏DNA的抗生素类抗癌药,可使细胞DNA解聚,抑制增生细胞的DNA的复制。小鼠静脉注射LD50为5ml/kg。

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