2-Fluoroalkyl acetic acids were converted to their corresponding carbonyl chlorides,which was then reacted with o-amino benzaldehyde and ammonia gas to give 3-(1-iminofluoroalkyl)-1H-qunolin-2-ones in moderate yields.

The resolution was 4 for the separation of the most difficult isomers such as o-toluidine and p-toluidine.

Indole has been prepared by the reaction of O-toluidine and formic acid to obtain N-formacyl-O-toluidine(O-toluidide),then in the presence of potassium hydroxide by toluone and O-toluidine used as water carrying reagent and solvent converted furter into potassium salt of O-toluidide,followed cyclization and hydrolysis.

Synthesize saframine O using o-toluidine as primer reactant by diazotization, coupling reaction, reduction reaction, and oxidation.

Novel green synthesis of o-nitrobenzaldehyde by oxidation of o-nitrotoluene with metal porphyrins as biomimetic catalysts;

Summary of the methods of preparing o-nitrobenzaldehyde;

Synthesis of o-nitrobenzaldehyde by indirect electrolytic oxidation;

The optimum condition for preparing o-hydroxybenzaldehyde by oxidating o-cresol in liquid oxygen is as follows: the mole ratio of methanol to o- cresol is 15, the amount of compounded catalysts of Cu(OAc)2 and Co (OAc)2 is 1% of o-cresol, stirring speed is 500 rotation per minute, reaction time and temperature are 10 hours and 80℃respectively, the mole ratio of sodium hydroxide to o-cresol is 3.

Starting from inexpensive phenylbutanol and o-hydroxybenzaldehyde,salmeterol was synthesized via a few steps,which is a unique long-acting selective β2-adrenoreceptor agonist.