1) long chain of RNA
RNA长链
1.
A novel cytidine derivate which was used as a monomer to prepare a long chain of RNA,ribonucleic acic(1),was synthesized from cytidine by selecting acylation of amide,selecting protection of hydroxy and phosphinyl acylation reaction in overall yield of 29.
以胞苷为原料,首先通过单乙酰化反应保护-NH2;再分别用二对甲氧基三苯甲基氯和氯甲氧基三异丙基硅烷保护5-′OH和2-′OH;被保护的胞苷经磷酰化反应合成了一种用于制备RNA长链的胞苷衍生物单体——N-乙酰基-5′-O-二对甲氧基三苯甲基-2′-O-三异丙基硅氧甲基-3′-O-双(N,N-二异丙基氨基)(2-氰乙氧基)磷基胞苷(1),总收率29。
2) dsRNA
双链RNA
1.
dsRNA-mediated Gene Silence and Antiviral Genetic Engineering;
双链RNA激发的植物基因沉默及其在植物育种上的应用
2.
dsRNA Isolation Method and Research of Plant Virology;
双链RNA技术与植物病毒研究
3.
In order to produce a marked effect in RNAi,21-25 nt siRNA,which is from dsRNA cutted by nucleinase,mediates and cuts homology mRNA.
它主要通过双链RNA(dsRNA)被核酸酶切割成21-25nt的小RNA(siRNA)发挥作用,由siRNA介导识别并靶向切割同源性靶mRNA分子而实现,需要有多种蛋白因子以及ATP参与,而且具有生物催化反应特征。
3) Double-stranded RNA
双链RNA
1.
RNA interference(RNAi) refers to the process where by double-stranded RNA(dsRNA) induces sequence-specific post-transcriptional gene silencing(PTGS).
RNA干扰(RNA i)是由双链RNA(doub le-stranded RNA,dsRNA)介导的、序列特异的转录后基因沉默机制,是一古老的细胞反应通路,其在抵抗病毒感染、抑制转座子活动、调控内源性基因表达等方面发挥重要作用。
2.
Putting double-stranded RNA into cell could cause homologous genes silencing.
将双链RNA导入细胞内会引起与其同源的基因的沉默,这种现象称为RNA干扰(RNA interference,RNAi)。
3.
RNA interference degrades mRNA specifically and potently though the mediation of corresponding double-stranded RNA and leads to post-transcriptional gene silencing .
RNA干涉是通过双链RNA的介导特异性地降解相应序列的mRNA,从而导致转录后水平的基因沉默,这一过程在拟南芥、线虫和真菌等多种模式植物中发现。
4) Double stranded RNA
双链RNA
1.
They are both directed by double stranded RNA.
基因沉默分为转录基因沉默和转录后基因沉默 ,二者都通过双链RNA介导 。
2.
Cytoplasmic polyhedrosis viruses (CPVs)(Reoviridae: Cypovirus ) are icosahedral particles with a segmented double stranded RNA genome.
质多角体病毒隶属呼肠孤病毒科质多角体病毒属 ,病毒粒子为二十面体球形颗粒 ,具有 3~ 5种结构蛋白 ,基因组由10或 11个节段双链RNA构成。
6) Short interfering RNA
短链RNA
1.
RNAi is the process that double-stranded RNA induces the homology-dependent degradation of cognate mRNA mediated by 21-23 nucleotide short interfering RNA ( siRNA ) .
RNA干扰(RNAi)技术是近年来发展起来的一种阻抑基因表达的新方法,其主要通过21-23nt短链RNA(siRNA)引起同源基因的mRNA降解,而使目的基因表达下降。
补充资料:RNA replicase
分子式:
CAS号:
性质:一种依赖于RNA的RNA聚合酶,它以RNA为模板,催化由核苷三磷酸合成RNA。
CAS号:
性质:一种依赖于RNA的RNA聚合酶,它以RNA为模板,催化由核苷三磷酸合成RNA。
说明:补充资料仅用于学习参考,请勿用于其它任何用途。
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