2) DNA break
DNA断裂
1.
To evaluate the toxic effects of bisphenol A(BPA)on aquatic organism,different developed stages of zebrafish(embryo,larva and adult fish) were exposed to BPA solution,and the DNA break determination was done on zebrafish embryo.
结果显示:斑马鱼成鱼24h的LC50(8·00—10·00mg·l-1)比胚胎(16·4±0·40mg·l-1)低,表明斑马鱼成鱼更适用于急性毒性试验,而胚胎更能体现出亚急性效应和遗传效应;在5·00mg·l-1的BPA中连续暴露48h后,胚胎和成鱼体内的BPA含量分别为373·57±39·76μg·g-1和155·78±17·97μg·g-1,即胚胎在5·00mg·l-1BPA溶液中的蓄积能力大约是成鱼的两倍;DNA断裂检测表明BPA对斑马鱼胚胎的DNA造成了一定程度的损伤。
2.
Results:All three platinum-species drugs could cause DNA break of pBR322 plasmid.
方法 :用琼脂糖凝胶电泳和凝胶成像分析方法结果 :顺铂、卡铂、双环铂均可诱发 pBR322质粒DNA断裂 ,对质粒DNA的半数致断剂量分别为33。
3) DNA breakage
DNA断裂
1.
Study on mechanism of formaldehyde-induced DNA breakage and repair;
甲醛致DNA断裂作用的机制及修复的研究
4) DNA strand breaks
DNA断裂
1.
18?mg/m~3 formaldehyde exposure could induce observably the DNA strand breaks occupational exposure populations peripheral hemocyte,whereas no significant was found in the frequency of micronucleus occurrence.
结论甲醛可导致接触工人外周血白细胞DNA发生明显断裂损伤,其带来的遗传损伤不容忽视,DNA断裂可能是其致癌机制之一。
5) DNA damage
DNA断裂
1.
In laboratory we use comet assay to evaluate DNA damage in lymphocytes of these people.
目的: 研究和田地区洛浦县长寿与非长寿家族的DNA断裂水平的基础值及其相关因素。
2.
Objective] To study the mutagenicity and DNA damage of genistein.
GEN达到90 μmol/L浓度时作用18h ,可导致CHL细胞和SMMC 772 1肝癌细胞DNA断裂,但CHL细胞各处理组间CAT和SOD差异都无显著性。
6) DNA cleavage agent
DNA断裂剂
补充资料：DNA分子花窗(沿B―DNA轴线方向看)
[图]
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条