Five effective and commonly used bioassay methods including uterine growth assay, vitellogenin of liver cells assay, MCF-7 cells assay, recombinant yeast assay and yeast two-hybrid assay were reviewed, and their applications in recent research on estrogens in environment were also discussed.

Objective: To evaluate the effects of levonorgestrol-releasing intrauterine system (LNG-IUS) for treatment of endometrium hyperplasia.

Method A cohort of 50 infertile women with pregnant failures in COH cycle due to poor endometrial development underwent the treatment by oral administration of viagra 50 mg per day from cycle 7～8 d to the day that endometrial thickness reached 8.

Expression of PR, PR-B and the serum level of E_2 , P in endometrial hyperplasia;

Expression of P27 in endometrial hyperplasia and endometrial adenocarcinoma and its Significance;

Objective: The aim of this study was to detect the expression of cyclooxygenase-2(COX-2) in tamoxifen-associated endometrial hyperplasia(tamoxifen-associated "high-risk endometrium") and investigate the effect of celecoxib,a selective COX-2 inhibitor on human endometrioid adenocarcinoma cells(HEC-1-B),thereby investigate the feasibility and mechanism of celecoxib on chemoprevention and treatment.