1) difluoromethylation
二氟甲醚化反应
1.
Methods 7,4′-di-difluoromethoxy-5-hythoxy isoflavone(2),4′-difluoromethoxy-5,7-dihythoxy isoflavone(3) and 7-difluoromethoxy-4′,5-dihythoxy isoflavone(4) were synthesized from genistein and HCF2Cl by difluoromethylation;7-difluoromethoxy-4′,5-dihythoxy isoflavone(5) and 4′-difluoromethoxy-5,7dimethoxy isoflavone(6) were synthesized from compounds(3) and(4) by methylation.
方法金雀异黄素与HCF2Cl、NaOH在水和二氧六环的混合液中发生二氟甲醚化反应,生成7,4′-二-二氟甲氧基-5-羟基异黄酮(2)、7-二氟甲氧-基5,4′-二羟基异黄酮(3)和4′-二氟甲氧基-5,7-二羟基异黄酮(4),再经甲醚化反应得到7-二氟甲氧基-5,4′-二甲氧基异黄酮(5)和4′-二氟甲氧基-5,7-二甲氧基异黄酮(6)。
3) etherification
醚化反应
1.
Model for etherification kinetics of pyrocatechol and methallyl chloride;
邻苯二酚与甲代烯丙基氯的醚化反应动力学
2.
Advances in the catalysts for synthesis of ethylene glycol ethers via etherification;
醚化反应法合成乙二醇醚催化剂研究进展
3.
Monoetherification of Hydroquinone Under the Action of Al_2O_3-supported K_2CO_3 Reagent;
对苯二酚在K_2CO_3-Al_2O_3负载型碱试剂作用下的单醚化反应
4) fluorination reaction
氟化反应
1.
Arylamine diazotization, thermal decomposition, halogen exchange for aromatic fluoride preparation, four kinds of commonly used phase transfer catalysts crown ether, quaternary ammonium salt, tetraphenyl phosphonium salt, polyethylene glycol and their applications in fluorination reaction are introduced.
介绍芳香氟化物制备方法,芳胺重氮化/热分解法、卤素交换法,氟化反应中4种常用的相转移催化剂冠醚、季铵盐、四苯基膦盐、聚乙二醇,及在氟化反应中的应用。
2.
A facile preparation of N phenyltetrafluorophthalimide starting from tetrachlorophthalic anhydride via imidation and fluorination reactions was described.
采用氟化钾为氟化剂 ,研究了氟化反应过程中相转移催化剂、溶剂、反应时间对四氟产物转化率和产率的影响 ,实验证明以DMF为溶剂 ,加入相转移催化剂PEG - 60 0 0 ,温度控制在 1 50℃ ,反应8h ,收率可达 86%。
5) Fluorination
[英][,flu:əri'neiʃən] [美][,flʊərɪ'neʃən]
氟化反应
1.
The application of phase transfer catalysis in fluorination of halo-aromatic compounds,mechanism,variety and reaction condition of fluorination are reviewed in this article.
从相转移催化剂的种类、原理、反应条件以及它在卤代芳香族化合物氟化反应中的应用等方面对相转移催化剂的作用进行概括和总结。
2.
Fluorobenzonitrile(4 FBN) was prepared by fluorination of 4 chlorobenzonitrile(4 CBN) with potassium fluoride using 1,3 dimethyl 2 imidazolidone (DMI) as a non polar solvent.
以 4 氯苯甲腈 ( 4 CBN)和无水氟化钾为原料 ,1,3 二甲基 2 咪唑啉酮 (DMI)为反应介质 ,经氟化反应合成了 4 氟苯甲腈 ( 4 FBN)。
3.
Several applications of triethylamine tris(hydrofluoride) to organic synthesis are summarized according to reaction type, especially for nucleophilic substitution, the ring-opening fluorination reaction of epoxide, electrophilic addition, desilylation reaction and so on.
氟化反应在有机合成中有着广泛的应用,三乙胺三(氟化氢)作为氟化试剂有着其它氟化试剂所无法比拟的优越性。
6) fluoridation
[英][,flɔ:rɪ'deɪʃn] [美]['flɔrə'deʃən]
氟化反应
1.
Study on the Synthesis of Calixarenes and Their Behavior as PTC in Fluoridation;
杯芳烃化合物的合成及其在氟化反应中的相转移催化作用
补充资料:甲醚
分子式C2H6O,分子量46.07。亦称二甲醚。结构简式CH3-O-CH3,无色可燃性气体或压缩液体。有乙醚气味,熔点-138.5℃,沸点-24.5℃。溶于水和乙醇。用作溶剂、冷冻剂等。可由甲醇脱水制得。
说明:补充资料仅用于学习参考,请勿用于其它任何用途。
参考词条