1) Pharmacophore model
药效团模型
1.
3D - database searching based on pharmacophore model of protox inhibitors;
利用原卟啉原氧化酶抑制剂药效团模型进行数据库搜索
2.
3D-database searching based on ALS inhibitors' pharmacophore model;
基于ALS抑制剂药效团模型的数据库搜索
3.
Construction of pharmacophore model of PARP-1 inhibitor;
聚腺苷二磷酸核糖聚合酶-1抑制剂药效团模型的建立
2) Pharmacophore
['fɑ:məkəfɔ:]
药效团模型
1.
Construction of the pharmacophore model of acetylcholinesterase inhibitor;
乙酰胆碱酯酶抑制剂药效团模型的构建(英文)
2.
Pharmacophore map (active conformation or alignment rules) for inhibitors of angiotensin converting enzyme (ACE) were defined by Constraints Search.
文章利用限制性构象搜寻 (ConstraintsSearch) ,确定了血管紧张素转化酶 (ACE)抑制剂的药效团模型 (活性构象或重叠规则 )。
3.
Based on the pharmacophore model of inhibiting terpenoids of GABA_A receptor of houseflies built by DISCOtech method,the inquiry structure for 3D database searching was built and then searched in 3D Traditional Chinese Medicines Database(TCMD)by 3DFS software.
用距离比较法(DISCOtech)构建的家蝇GABA_A受体萜类抑制剂药效团模型为基础建立了提问结构,以三维数据库搜索软件3DFS为工具,在三维结构中草药数据库(TCMD)中进行了搜索。
3) Pharmacophore
['fɑ:məkəfɔ:]
药效基团模型
4) Pharmacokinetics-pharmacodynamics(PK-PD) models
药动-药效模型
5) pharmacophore
['fɑ:məkəfɔ:]
药效团
1.
3D-QSAR and Pharmacophore Modeling of Growth Hormone Secretagogues;
促生长激素释放素三维定量构效关系及药效团模型
2.
Strategy of molecular drug design:pharmacophore and scaffold hopping;
药物分子设计的策略:论药效团和骨架迁越
3.
Study of concerted mechanism between P-glycoprotein and cytochrome P4503A4 by 3D-pharmacophore modeling;
基于3D-药效团的P糖蛋白和细胞色素P4503A4的协同作用机理研究
6) pharmacophore
['fɑ:məkəfɔ:]
药效基团
1.
Overview of studies on the anti-tumour pharmacophore of traditional Chinese medicines;
中药抗肿瘤有效成分的药效基团研究概况
2.
Present paper elucidates the following aspects; evolution of chemical classes of insecticides that act on insect nAChRs, structure and function of nAChRs, structure - activity of nicotine analogs, the structure modified and selectivity of neonicotinoid insecticides, and the pharmacophore of neonicotinoids.
本文就以下几方面作了详细的阐述:作用于昆虫nAChRs的各类化学杀虫剂的演绎,nAChRs的结构与活性,烟碱类似物的结构与活性,新烟碱类杀虫剂的结构修饰及其选择性,以及新烟碱类的药效基团。
3.
Functional fragments contain structural elements known as pharmacophores which generate the bioactivity of the drugs,while structural fragments assemble the functional fragments into a specific skeleton also crucial for the activity.
功能性分子片段包含药物产生生物活性所必须的结构单元(简称药效基团);而结构性分子片段则是将功能性分子片段连接起来从而形成特定结构的分子骨架。
补充资料：刓团
1.圆滑，无棱角貌。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条